{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Morozova V"],"funding":["Ministry of Science and Higher Education of Russian Federation"],"pagination":["2733"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9780818"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(12)"],"pubmed_abstract":["<i>Aeromonas popoffii</i> is one of the environmental <i>Aeromonas</i> species. A number of factors of virulence have been described for this species and it has been reported as a causative agent of urinary tract infection. The first <i>A. popoffii</i> bacteriophage AerP_220 along with its host strain <i>A. popoffii</i> CEMTC 4062 were isolated from river water. The phage has a podovirus morphotype, shows a narrow host range and is lytic against the host strain. The AerP_220 genome comprises 45,207 bp and does not contain genes responsible for antibiotic resistance and toxin production. Fifty-nine co-directional putative ORFs were found in the AerP_220 genome. Thirty-three ORFs encoded proteins with predicted functions; the products of 26 ORFs were hypothetical proteins. AerP_220 genome analysis revealed that this phage can be considered a novel species within the <i>Autographiviridae</i> family. Comparative genomic and proteomic analysis revealed that AerP_220 along with the <i>Aeromonas</i> phage vB_AspA_Tola (OM913599) are members of a new putative <i>Tolavirus</i> genus in the family <i>Autographiviridae</i>. The <i>Gajwadongvirus</i> and proposed <i>Tolavirus</i> genera along with Pantoea phage Nufs112 and phage Reminis could form a new <i>Tolavirinae</i> subfamily within the <i>Autographiviridae</i> family."],"journal":["Viruses"],"pubmed_title":["A Novel <i>Aeromonas popoffii</i> Phage AerP_220 Proposed to Be a Member of a New <i>Tolavirus</i> Genus in the <i>Autographiviridae</i> Family."],"pmcid":["PMC9780818"],"funding_grant_id":["075-15-2021-1085"],"pubmed_authors":["Poletaeva Y","Jdeed G","Tikunov A","Kozlova Y","Morozova V","Ushakova T","Zhirakovskaia E","Bardasheva A","Ryabchikova E","Tikunova NV"],"additional_accession":[]},"is_claimable":false,"name":"A Novel <i>Aeromonas popoffii</i> Phage AerP_220 Proposed to Be a Member of a New <i>Tolavirus</i> Genus in the <i>Autographiviridae</i> Family.","description":"<i>Aeromonas popoffii</i> is one of the environmental <i>Aeromonas</i> species. A number of factors of virulence have been described for this species and it has been reported as a causative agent of urinary tract infection. The first <i>A. popoffii</i> bacteriophage AerP_220 along with its host strain <i>A. popoffii</i> CEMTC 4062 were isolated from river water. The phage has a podovirus morphotype, shows a narrow host range and is lytic against the host strain. The AerP_220 genome comprises 45,207 bp and does not contain genes responsible for antibiotic resistance and toxin production. Fifty-nine co-directional putative ORFs were found in the AerP_220 genome. Thirty-three ORFs encoded proteins with predicted functions; the products of 26 ORFs were hypothetical proteins. AerP_220 genome analysis revealed that this phage can be considered a novel species within the <i>Autographiviridae</i> family. Comparative genomic and proteomic analysis revealed that AerP_220 along with the <i>Aeromonas</i> phage vB_AspA_Tola (OM913599) are members of a new putative <i>Tolavirus</i> genus in the family <i>Autographiviridae</i>. The <i>Gajwadongvirus</i> and proposed <i>Tolavirus</i> genera along with Pantoea phage Nufs112 and phage Reminis could form a new <i>Tolavirinae</i> subfamily within the <i>Autographiviridae</i> family.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2026-04-08T11:00:09.508Z","creation":"2024-11-08T14:39:04.82Z"},"accession":"S-EPMC9780818","cross_references":{"pubmed":["36560737"],"doi":["10.3390/v14122733"]}}