{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(12)"],"submitter":["Camargo M"],"pubmed_abstract":["The cervical microbiota is essential in female sexual health, and its altered states seem to have a central role in the dynamic of high-risk papillomavirus (hrHPV) infections. This study aimed to evaluate the variation in bacterial communities' compositions according to hrHPV. We collected two samples per woman, with a difference of 12 ± 1 months between them, and performed a follow-up on 66 of these women. The viral load (VL) of the hrHPV was estimated by quantitative PCR (qPCR), then it was normalized (using the <i>HMBS</i> gene as reference) and transformed to the Log<sub>10</sub> scale to facilitate the interpretation. The VL was categorized as Negative, without hrHPV copies; Low, less than 10<sup>0</sup> hrHPV copies; Medium, between 10<sup>0</sup> to 10<sup>2</sup> hrHPV copies; and "],"journal":["Viruses"],"pagination":["2674"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9781391"],"repository":["biostudies-literature"],"pubmed_title":["Changes in the Cervical Microbiota of Women with Different High-Risk Human Papillomavirus Loads."],"pmcid":["PMC9781391"],"pubmed_authors":["Patarroyo ME","Sanchez R","Vega L","Munoz M","Camargo M","Ramirez JD","Patarroyo MA"],"additional_accession":[]},"is_claimable":false,"name":"Changes in the Cervical Microbiota of Women with Different High-Risk Human Papillomavirus Loads.","description":"The cervical microbiota is essential in female sexual health, and its altered states seem to have a central role in the dynamic of high-risk papillomavirus (hrHPV) infections. This study aimed to evaluate the variation in bacterial communities' compositions according to hrHPV. We collected two samples per woman, with a difference of 12 ± 1 months between them, and performed a follow-up on 66 of these women. The viral load (VL) of the hrHPV was estimated by quantitative PCR (qPCR), then it was normalized (using the <i>HMBS</i> gene as reference) and transformed to the Log<sub>10</sub> scale to facilitate the interpretation. The VL was categorized as Negative, without hrHPV copies; Low, less than 10<sup>0</sup> hrHPV copies; Medium, between 10<sup>0</sup> to 10<sup>2</sup> hrHPV copies; and ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-04-08T10:56:48.204Z","creation":"2024-11-15T17:28:06.469Z"},"accession":"S-EPMC9781391","cross_references":{"pubmed":["36560678"],"doi":["10.3390/v14122674"]}}