{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Zhao J"],"pubmed_abstract":["<h4>Background</h4>It is generally believed that complement system is strongly associated with the risk of nonalcoholic fatty liver disease (NAFLD). However, complement system contains a variety of complement components, and the relationship between complement components and the risk and severity of NAFLD is inconsistent. The aim of this meta-analysis was to evaluate the association of complement components with the risk and severity of NAFLD.<h4>Methods</h4>We searched PubMed, Embase, Cochrane Library, Google Scholar, Scopus, and ZhiWang Chinese databases from inception to May 2022 for observational studies reporting the risk of NAFLD with complement components. Random-effects meta-analysis was used to obtain pooled estimates of the effect due to heterogeneity.<h4>Results</h4>We identifie"],"journal":["Frontiers in immunology"],"pagination":["1054159"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9782972"],"repository":["biostudies-literature"],"pubmed_title":["Association of complement components with the risk and severity of NAFLD: A systematic review and meta-analysis."],"pmcid":["PMC9782972"],"pubmed_authors":["Liu Y","Fan X","Gao L","Han J","Zhao J","Lu P","Wang Z","Wu Y","Cheng Y","Wu X","Shi Y"],"additional_accession":[]},"is_claimable":false,"name":"Association of complement components with the risk and severity of NAFLD: A systematic review and meta-analysis.","description":"<h4>Background</h4>It is generally believed that complement system is strongly associated with the risk of nonalcoholic fatty liver disease (NAFLD). However, complement system contains a variety of complement components, and the relationship between complement components and the risk and severity of NAFLD is inconsistent. The aim of this meta-analysis was to evaluate the association of complement components with the risk and severity of NAFLD.<h4>Methods</h4>We searched PubMed, Embase, Cochrane Library, Google Scholar, Scopus, and ZhiWang Chinese databases from inception to May 2022 for observational studies reporting the risk of NAFLD with complement components. Random-effects meta-analysis was used to obtain pooled estimates of the effect due to heterogeneity.<h4>Results</h4>We identifie","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T21:54:42.894Z","creation":"2024-11-20T22:40:59.874Z"},"accession":"S-EPMC9782972","cross_references":{"pubmed":["36569882"],"doi":["10.3389/fimmu.2022.1054159"]}}