biostudies-literatureUnknown20(12)D'Angelo CThe development of new approaches to prevent microbial surface adhesion and biofilm formation is an emerging need following the growing understanding of the impact of biofilm-related infections on human health. <i>Staphylococcus epidermidis</i>, with its ability to form biofilm and colonize biomaterials, represents the most frequent causative agent involved in infections of medical devices. In the research of new anti-biofilm agents against <i>S. epidermidis</i> biofilm, Antarctic marine bacteria represent an untapped reservoir of biodiversity. In the present study, the attention was focused on <i>Psychrobacter sp</i>. TAE2020, an Antarctic marine bacterium that produces molecules able to impair the initial attachment of <i>S. epidermidis</i> strains to the polystyrene surface. The setup oMarine drugs747https://www.ebi.ac.uk/biostudies/studies/S-EPMC9785100biostudies-literatureCATASAN Is a New Anti-Biofilm Agent Produced by the Marine Antarctic Bacterium <i>Psychrobacter</i> sp. TAE2020.PMC9785100Melchiorre CCasillo ALauro CTutino MLD'Angelo CCorsaro MMParrilli ECarpentieri AfalseCATASAN Is a New Anti-Biofilm Agent Produced by the Marine Antarctic Bacterium <i>Psychrobacter</i> sp. TAE2020.The development of new approaches to prevent microbial surface adhesion and biofilm formation is an emerging need following the growing understanding of the impact of biofilm-related infections on human health. <i>Staphylococcus epidermidis</i>, with its ability to form biofilm and colonize biomaterials, represents the most frequent causative agent involved in infections of medical devices. In the research of new anti-biofilm agents against <i>S. epidermidis</i> biofilm, Antarctic marine bacteria represent an untapped reservoir of biodiversity. In the present study, the attention was focused on <i>Psychrobacter sp</i>. TAE2020, an Antarctic marine bacterium that produces molecules able to impair the initial attachment of <i>S. epidermidis</i> strains to the polystyrene surface. The setup o2022-01-01T00:00:00Z2022 Nov2026-04-08T18:26:22.28Z2025-04-04T12:10:22.764ZS-EPMC97851003654789410.3390/md20120747