<HashMap><database>biostudies-literature</database><scores/><additional><submitter>Stahlmann K</submitter><funding>Sixth Framework Programme</funding><funding>Seventh Framework Programme</funding><funding>Forskningsrådet om Hälsa, Arbetsliv och Välfärd</funding><pagination>e12963</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC9786348</full_dataset_link><repository>biostudies-literature</repository><omics_type>Unknown</omics_type><volume>17(12)</volume><pubmed_abstract>&lt;h4>Background&lt;/h4>Living in single parent and blended families or as an only child-compared to living in two-parent biological families or with siblings, respectively-is associated with a higher body mass index (BMI) in cross-sectional studies. However, longitudinal research addressing the children's BMI in this context is scarce. Further, little is known about the association between family structure and metabolic health.&lt;h4>Objectives&lt;/h4>This study aimed at investigating the association between both aspects of family structure with BMI and a metabolic score (MetS).&lt;h4>Methods&lt;/h4>Cross-sectional data from 7804 children participating in the European multi-center I.Family study (2013/2014) and longitudinal data from 5621 children who also participated previously in the IDEFICS study (2007-2010) were used. Family structure was assessed by a detailed interview. BMI z-score and the MetS were based on measured anthropometry, blood pressure, high-density lipoprotein, blood glucose, and triglycerides. Linear regressions were performed to model associations between family structure with BMI and MetS.&lt;h4>Results&lt;/h4>Children from single-parent families had higher BMI z-scores in the cross-sectional (β = 0.09, 95% confidence interval [CI]: 0.001 to 0.18) and longitudinal analyses compared to those from two-parent families. Cross-sectionally, the number of siblings was associated with lower BMI z-scores (β = -0.07, 95% CI: -0.10 to -0.03) and lower MetS (β = -0.14, 95% CI: -0.26 to -0.01). Longitudinally, only children between baseline and follow-up had higher BMI z-scores at follow-up (β = 0.07, 95% CI: 0.01 to 0.14) compared to stable siblings.&lt;h4>Conclusion&lt;/h4>Obesity prevention measures should focus on single-parent households and families with an only child.</pubmed_abstract><journal>Pediatric obesity</journal><pubmed_title>Family structure in relation to body mass index and metabolic score in European children and adolescents.</pubmed_title><pmcid>PMC9786348</pmcid><funding_grant_id>016181</funding_grant_id><funding_grant_id>2014‐01994</funding_grant_id><funding_grant_id>266044</funding_grant_id><pubmed_authors>IDEFICS/I.Family consortia</pubmed_authors><pubmed_authors>Stahlmann K</pubmed_authors><pubmed_authors>Kaprio J</pubmed_authors><pubmed_authors>Lauria F</pubmed_authors><pubmed_authors>Moreno LA</pubmed_authors><pubmed_authors>Bogl LH</pubmed_authors><pubmed_authors>Molnar D</pubmed_authors><pubmed_authors>Mehlig K</pubmed_authors><pubmed_authors>Klosowska JC</pubmed_authors><pubmed_authors>Wolters M</pubmed_authors><pubmed_authors>Hunsberger M</pubmed_authors><pubmed_authors>Bornhorst C</pubmed_authors><pubmed_authors>Hebestreit A</pubmed_authors><pubmed_authors>Veidebaum T</pubmed_authors><pubmed_authors>Lissner L</pubmed_authors><pubmed_authors>Solea A</pubmed_authors></additional><is_claimable>false</is_claimable><name>Family structure in relation to body mass index and metabolic score in European children and adolescents.</name><description>&lt;h4>Background&lt;/h4>Living in single parent and blended families or as an only child-compared to living in two-parent biological families or with siblings, respectively-is associated with a higher body mass index (BMI) in cross-sectional studies. However, longitudinal research addressing the children's BMI in this context is scarce. Further, little is known about the association between family structure and metabolic health.&lt;h4>Objectives&lt;/h4>This study aimed at investigating the association between both aspects of family structure with BMI and a metabolic score (MetS).&lt;h4>Methods&lt;/h4>Cross-sectional data from 7804 children participating in the European multi-center I.Family study (2013/2014) and longitudinal data from 5621 children who also participated previously in the IDEFICS study (2007-2010) were used. Family structure was assessed by a detailed interview. BMI z-score and the MetS were based on measured anthropometry, blood pressure, high-density lipoprotein, blood glucose, and triglycerides. Linear regressions were performed to model associations between family structure with BMI and MetS.&lt;h4>Results&lt;/h4>Children from single-parent families had higher BMI z-scores in the cross-sectional (β = 0.09, 95% confidence interval [CI]: 0.001 to 0.18) and longitudinal analyses compared to those from two-parent families. Cross-sectionally, the number of siblings was associated with lower BMI z-scores (β = -0.07, 95% CI: -0.10 to -0.03) and lower MetS (β = -0.14, 95% CI: -0.26 to -0.01). Longitudinally, only children between baseline and follow-up had higher BMI z-scores at follow-up (β = 0.07, 95% CI: 0.01 to 0.14) compared to stable siblings.&lt;h4>Conclusion&lt;/h4>Obesity prevention measures should focus on single-parent households and families with an only child.</description><dates><release>2022-01-01T00:00:00Z</release><publication>2022 Dec</publication><modification>2024-11-19T16:56:03.493Z</modification><creation>2024-11-19T16:56:03.493Z</creation></dates><accession>S-EPMC9786348</accession><cross_references><pubmed>35950257</pubmed><doi>10.1111/ijpo.12963</doi></cross_references></HashMap>