{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xu W"],"funding":["Capital's Funds for Research and Application of Clinical Diagnosis and Treatment Technology","High-level Hospital Clinical Research Funds","Capital's Funds for Health Improvement and Research"],"pagination":["426"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9788599"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(12)"],"pubmed_abstract":["<h4>Aims</h4>Patients with left ventricular noncompaction (LVNC) are at risk of thromboembolism. The relationship between left atrial diameter (LAD), a robust predictor for thrombosis, and LVNC is unclear. The purpose of this study was to explore the effect of LAD on the thrombotic risk in LVNC.<h4>Methods</h4>In this retrospective cohort study, 320 patients with imaging characteristics of LVNC were included for statistical analysis. The primary endpoint was a composite event of intracardiac thrombi and stroke or transient ischemic attack (TIA). The secondary endpoints were intracardiac thrombi and stroke/TIA.<h4>Results</h4>The 320 included patients (211 [65.9%] men, median age: 45 years [interquartile range: 30-57]) were divided into LAD1 (&lt;43 mm, <i>n</i> = 157) and LAD2 (≥43 mm, <i>"],"journal":["Journal of cardiovascular development and disease"],"pubmed_title":["Left Atrial Diameter and the Risk of Thromboembolism in Patients with Left Ventricular Noncompaction."],"pmcid":["PMC9788599"],"funding_grant_id":["2022-GSP-GG-26","Z191100006619121","2018-2-4031"],"pubmed_authors":["Yang Y","Zhu J","Tan J","Xu W","Wang J","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Left Atrial Diameter and the Risk of Thromboembolism in Patients with Left Ventricular Noncompaction.","description":"<h4>Aims</h4>Patients with left ventricular noncompaction (LVNC) are at risk of thromboembolism. The relationship between left atrial diameter (LAD), a robust predictor for thrombosis, and LVNC is unclear. The purpose of this study was to explore the effect of LAD on the thrombotic risk in LVNC.<h4>Methods</h4>In this retrospective cohort study, 320 patients with imaging characteristics of LVNC were included for statistical analysis. The primary endpoint was a composite event of intracardiac thrombi and stroke or transient ischemic attack (TIA). The secondary endpoints were intracardiac thrombi and stroke/TIA.<h4>Results</h4>The 320 included patients (211 [65.9%] men, median age: 45 years [interquartile range: 30-57]) were divided into LAD1 (&lt;43 mm, <i>n</i> = 157) and LAD2 (≥43 mm, <i>","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-04T08:00:13.865Z","creation":"2025-04-04T08:00:13.865Z"},"accession":"S-EPMC9788599","cross_references":{"pubmed":["36547423"],"doi":["10.3390/jcdd9120426"]}}