biostudies-literatureUnknown100(8)Govers BMLandelijke Stichting voor Blinden en SlechtziendenStichting Steunfonds UitzichtOogfondsStichting A.F. Deutman Oogheelkunde Researchfonds<h4>Purpose</h4>To compare the treatment success of air with fluorinated gas (20% SF₆ or 14% C₃ F₈ ) tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment.<h4>Methods</h4>A retrospective cohort study comprised of 1023 consecutive primary retinal detachment cases between 2014 and 2020. We employed a univariate multivariable binary logistic regression model.<h4>Results</h4>We used intraocular gas tamponades in 872 cases with PVR grade B or lower: air tamponade was used in 414 eyes and 458 eyes were treated with a type of fluorinated gas tamponade. There was no significant difference in the type of tamponade with regard to the re-detachment rate (95% CI -1.0% and 4.1%). Additionally, also in the subgroup of rhegmatogenous retinal detachments with inferior located retinal defects we found no significant difference between the two types of tamponade (p = 0.54 Fisher's exact). The multivariable model, which included tamponade, PVR grade, a retinal detachment involving the 6 o'clock position and age as covariates, also showed no significant effect of tamponade choice on treatment success (OR 0.5, 95% 0.2-1.0, p = 0.10).<h4>Conclusion</h4>We found no difference in treatment success with air tamponade versus fluorinated gas tamponades in the repair of primary retinal detachments, this also includes inferiorly located retinal tears and detachments.Acta ophthalmologicae1600-e1605https://www.ebi.ac.uk/biostudies/studies/S-EPMC9790619biostudies-literatureAir versus fluorinated gas tamponades in pars plana vitrectomy treatment for primary rhegmatogenous retinal detachment.PMC9790619Govers BMLamers MPMKlevering BJKeijser SfalseAir versus fluorinated gas tamponades in pars plana vitrectomy treatment for primary rhegmatogenous retinal detachment.<h4>Purpose</h4>To compare the treatment success of air with fluorinated gas (20% SF₆ or 14% C₃ F₈ ) tamponade in pars plana vitrectomy for primary rhegmatogenous retinal detachment.<h4>Methods</h4>A retrospective cohort study comprised of 1023 consecutive primary retinal detachment cases between 2014 and 2020. We employed a univariate multivariable binary logistic regression model.<h4>Results</h4>We used intraocular gas tamponades in 872 cases with PVR grade B or lower: air tamponade was used in 414 eyes and 458 eyes were treated with a type of fluorinated gas tamponade. There was no significant difference in the type of tamponade with regard to the re-detachment rate (95% CI -1.0% and 4.1%). Additionally, also in the subgroup of rhegmatogenous retinal detachments with inferior located retinal defects we found no significant difference between the two types of tamponade (p = 0.54 Fisher's exact). The multivariable model, which included tamponade, PVR grade, a retinal detachment involving the 6 o'clock position and age as covariates, also showed no significant effect of tamponade choice on treatment success (OR 0.5, 95% 0.2-1.0, p = 0.10).<h4>Conclusion</h4>We found no difference in treatment success with air tamponade versus fluorinated gas tamponades in the repair of primary retinal detachments, this also includes inferiorly located retinal tears and detachments.2022-01-01T00:00:00Z2022 Dec2025-04-04T12:10:08.717Z2025-04-04T12:10:08.717ZS-EPMC97906193535249810.1111/aos.15144