{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gibbons C"],"funding":["Horizon 2020 Framework Programme","Steno Diabetes Center Copenhagen (SDCC)","SWEET"],"pagination":["e063903"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9791453"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(12)"],"pubmed_abstract":["<h4>Introduction</h4>Intake of free sugars in European countries is high and attempts to reduce sugar intake have been mostly ineffective. Non-nutritive sweeteners and sweetness enhancers (S&SEs) can maintain sweet taste in the absence of energy, but little is known about the impact of acute and repeated consumption of S&SE in foods on appetite. This study aims to evaluate the effect of acute and repeated consumption of two individual S&SEs and two S&SE blends in semisolid and solid foods on appetite and related behavioural, metabolic and health outcomes.<h4>Methods and analysis</h4>A work package of the SWEET Project; this study consists of five double-blind randomised cross-over trials which will be carried out at five sites across four European countries, aiming to have n=213. Five food"],"journal":["BMJ open"],"pubmed_title":["Acute and repeated impact of sweeteners and sweetness enhancers in solid and semi-solid foods on appetite: protocol for a multicentre, cross-over, RCT in people with overweight/obesity - the SWEET Project."],"pmcid":["PMC9791453"],"funding_grant_id":["SDCC 3.G","774293"],"pubmed_authors":["Kjolbæk L","Blaak EE","Raben A","Harrold JA","Scott C","Normand M","Alligier M","Feskens E","Rannou C","Martinez JA","Finlayson G","Wilton M","Navas-Carretero S","Moshoyiannis H","Beaulieu K","Nazare JA","Halford JCG","Gibbons C","O'Hara B","O'Connor D","Hardman C","Hodgkins CE","Almiron-Roig E"],"additional_accession":[]},"is_claimable":false,"name":"Acute and repeated impact of sweeteners and sweetness enhancers in solid and semi-solid foods on appetite: protocol for a multicentre, cross-over, RCT in people with overweight/obesity - the SWEET Project.","description":"<h4>Introduction</h4>Intake of free sugars in European countries is high and attempts to reduce sugar intake have been mostly ineffective. Non-nutritive sweeteners and sweetness enhancers (S&SEs) can maintain sweet taste in the absence of energy, but little is known about the impact of acute and repeated consumption of S&SE in foods on appetite. This study aims to evaluate the effect of acute and repeated consumption of two individual S&SEs and two S&SE blends in semisolid and solid foods on appetite and related behavioural, metabolic and health outcomes.<h4>Methods and analysis</h4>A work package of the SWEET Project; this study consists of five double-blind randomised cross-over trials which will be carried out at five sites across four European countries, aiming to have n=213. Five food","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2026-07-14T16:06:11.873Z","creation":"2024-11-19T17:02:42.46Z"},"accession":"S-EPMC9791453","cross_references":{"pubmed":["36564114"],"doi":["10.1136/bmjopen-2022-063903"]}}