{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6"],"submitter":["Sicolo E"],"pubmed_abstract":["<h4>Background</h4>Mediastinal mass management may represent a real challenge for all the physicians who deal with it. Mediastinum, in fact, contains different vital structures which are often involved by growing neoplasms with increasing severity. Therefore, up to 60% of the patients with mediastinal mass are symptomatic, according to the structure involved. Different neoplasms may arise essentially from all mediastinal organs, whereas thymic epithelial tumors and lymphomas represent more than 90% of mediastinal tumors.<h4>Case description</h4>We report the first case described of a giant asymptomatic mediastinal mass in a 43-year-old male affected by Down syndrome (DS), turned out to be a thymoma, treated exclusively and successfully with radical surgery. Despite the absence of any sympt"],"journal":["Mediastinum (Hong Kong, China)"],"pagination":["39"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9792865"],"repository":["biostudies-literature"],"pubmed_title":["An asymptomatic giant AB thymoma in a patient with Down syndrome: a case report."],"pmcid":["PMC9792865"],"pubmed_authors":["Mastromarino MG","Lucchi M","Ali G","Sicolo E","Korasidis S","Bacchin D","Ambrogi MC","Aprile V","Ferrarello T"],"additional_accession":[]},"is_claimable":false,"name":"An asymptomatic giant AB thymoma in a patient with Down syndrome: a case report.","description":"<h4>Background</h4>Mediastinal mass management may represent a real challenge for all the physicians who deal with it. Mediastinum, in fact, contains different vital structures which are often involved by growing neoplasms with increasing severity. Therefore, up to 60% of the patients with mediastinal mass are symptomatic, according to the structure involved. Different neoplasms may arise essentially from all mediastinal organs, whereas thymic epithelial tumors and lymphomas represent more than 90% of mediastinal tumors.<h4>Case description</h4>We report the first case described of a giant asymptomatic mediastinal mass in a 43-year-old male affected by Down syndrome (DS), turned out to be a thymoma, treated exclusively and successfully with radical surgery. Despite the absence of any sympt","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T14:10:47.824Z","creation":"2025-04-04T14:10:47.824Z"},"accession":"S-EPMC9792865","cross_references":{"pubmed":["36582979"],"doi":["10.21037/med-22-8"]}}