biostudies-literatureUnknown22(1)Coeckelenbergh S<h4>Background</h4>During surgery, any mismatch between oxygen delivery (DO<sub>2</sub>) and consumption (VO<sub>2</sub>) can promote the development of postoperative complications. The respiratory exchange ratio (RER), defined as the ratio of carbon dioxide (CO<sub>2</sub>) production (VCO<sub>2</sub>) to VO<sub>2</sub>, may be a useful noninvasive tool for detecting inadequate DO<sub>2</sub>. The primary objective of this study was to test the hypothesis that RER measured during liver transplantation may predict postoperative morbidity. Secondary objectives were to assess the ability of other variables used to assess the DO<sub>2</sub>/VO<sub>2</sub> relationship, including arterial lactate, mixed venous oxygen saturation, and veno-arterial difference in the partial pressure of carbon diBMC anesthesiology405https://www.ebi.ac.uk/biostudies/studies/S-EPMC9795787biostudies-literatureIntraoperative measurement of the respiratory exchange ratio predicts postoperative complications after liver transplantation.PMC9795787Naili SThepault FMoussa MDuranteau JPham HLanteri Minet MCherqui DPellerin FDe Oliveira CCarrier FMRoullet SLaukaityte EToubal LKato HCoeckelenbergh SVan der Linden PJoosten ACiacio OVincent JLDesebbe OAmara YLe Canne CHerboulier LfalseIntraoperative measurement of the respiratory exchange ratio predicts postoperative complications after liver transplantation.<h4>Background</h4>During surgery, any mismatch between oxygen delivery (DO<sub>2</sub>) and consumption (VO<sub>2</sub>) can promote the development of postoperative complications. The respiratory exchange ratio (RER), defined as the ratio of carbon dioxide (CO<sub>2</sub>) production (VCO<sub>2</sub>) to VO<sub>2</sub>, may be a useful noninvasive tool for detecting inadequate DO<sub>2</sub>. The primary objective of this study was to test the hypothesis that RER measured during liver transplantation may predict postoperative morbidity. Secondary objectives were to assess the ability of other variables used to assess the DO<sub>2</sub>/VO<sub>2</sub> relationship, including arterial lactate, mixed venous oxygen saturation, and veno-arterial difference in the partial pressure of carbon di2022-01-01T00:00:00Z2022 Dec2025-04-05T15:41:38.029Z2025-04-05T15:41:38.029ZS-EPMC97957873657795410.1186/s12871-022-01949-2