{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Bogdanova T"],"pubmed_abstract":["<h4>Introduction</h4>A worldwide increase in the incidence of thyroid cancer during the last decades is largely due to papillary thyroid microcarcinomas (MPTCs), which are mostly low-risk tumors. In view of recent clinical recommendations to reduce the extent of surgery for low-risk thyroid cancer, and persisting uncertainty about the impact of radiation history, we set out to address whether clinicopathological characteristics and prognosis of post-Chornobyl MPTCs were changing with regard to: i) the latency period, ii) probability of causation (POC) of a tumor due to radiation, and iii) tumor size.<h4>Methods</h4>Patients (n = 465) aged up to 50 years at diagnosis who lived in April, 1986 in six northern, most radiocontaminated regions of Ukraine were studied.<h4>Results</h4>Latency peri"],"journal":["Frontiers in endocrinology"],"pagination":["1078258"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9796818"],"repository":["biostudies-literature"],"pubmed_title":["The relationship of the clinicopathological characteristics and treatment results of post-Chornobyl papillary thyroid microcarcinomas with the latency period and radiation exposure."],"pmcid":["PMC9796818"],"pubmed_authors":["Bolgov M","Masiuk S","Saenko VA","Chernyshov S","Yamashita S","Bogdanova T","Zurnadzhy L","Mitsutake N","Ito M","Tronko M","Rogounovitch TI"],"additional_accession":[]},"is_claimable":false,"name":"The relationship of the clinicopathological characteristics and treatment results of post-Chornobyl papillary thyroid microcarcinomas with the latency period and radiation exposure.","description":"<h4>Introduction</h4>A worldwide increase in the incidence of thyroid cancer during the last decades is largely due to papillary thyroid microcarcinomas (MPTCs), which are mostly low-risk tumors. In view of recent clinical recommendations to reduce the extent of surgery for low-risk thyroid cancer, and persisting uncertainty about the impact of radiation history, we set out to address whether clinicopathological characteristics and prognosis of post-Chornobyl MPTCs were changing with regard to: i) the latency period, ii) probability of causation (POC) of a tumor due to radiation, and iii) tumor size.<h4>Methods</h4>Patients (n = 465) aged up to 50 years at diagnosis who lived in April, 1986 in six northern, most radiocontaminated regions of Ukraine were studied.<h4>Results</h4>Latency peri","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-18T22:25:47.618Z","creation":"2025-04-07T10:13:33.661Z"},"accession":"S-EPMC9796818","cross_references":{"pubmed":["36589808"],"doi":["10.3389/fendo.2022.1078258"]}}