biostudies-literatureUnknown13Bogdanova T<h4>Introduction</h4>A worldwide increase in the incidence of thyroid cancer during the last decades is largely due to papillary thyroid microcarcinomas (MPTCs), which are mostly low-risk tumors. In view of recent clinical recommendations to reduce the extent of surgery for low-risk thyroid cancer, and persisting uncertainty about the impact of radiation history, we set out to address whether clinicopathological characteristics and prognosis of post-Chornobyl MPTCs were changing with regard to: i) the latency period, ii) probability of causation (POC) of a tumor due to radiation, and iii) tumor size.<h4>Methods</h4>Patients (n = 465) aged up to 50 years at diagnosis who lived in April, 1986 in six northern, most radiocontaminated regions of Ukraine were studied.<h4>Results</h4>Latency periFrontiers in endocrinology1078258https://www.ebi.ac.uk/biostudies/studies/S-EPMC9796818biostudies-literatureThe relationship of the clinicopathological characteristics and treatment results of post-Chornobyl papillary thyroid microcarcinomas with the latency period and radiation exposure.PMC9796818Bolgov MMasiuk SSaenko VAChernyshov SYamashita SBogdanova TZurnadzhy LMitsutake NIto MTronko MRogounovitch TIfalseThe relationship of the clinicopathological characteristics and treatment results of post-Chornobyl papillary thyroid microcarcinomas with the latency period and radiation exposure.<h4>Introduction</h4>A worldwide increase in the incidence of thyroid cancer during the last decades is largely due to papillary thyroid microcarcinomas (MPTCs), which are mostly low-risk tumors. In view of recent clinical recommendations to reduce the extent of surgery for low-risk thyroid cancer, and persisting uncertainty about the impact of radiation history, we set out to address whether clinicopathological characteristics and prognosis of post-Chornobyl MPTCs were changing with regard to: i) the latency period, ii) probability of causation (POC) of a tumor due to radiation, and iii) tumor size.<h4>Methods</h4>Patients (n = 465) aged up to 50 years at diagnosis who lived in April, 1986 in six northern, most radiocontaminated regions of Ukraine were studied.<h4>Results</h4>Latency peri2022-01-01T00:00:00Z20222025-04-18T22:25:47.618Z2025-04-07T10:13:33.661ZS-EPMC97968183658980810.3389/fendo.2022.1078258