{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Burnell M"],"funding":["The Eve Appeal","Medical Research Council","NIHR Biomedical Research Centre, University College London Hospitals","NHS Innovation Accelerator"],"pagination":["1970-1980"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9796935"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["129(12)"],"pubmed_abstract":["<h4>Objective</h4>Ashkenazi-Jewish (AJ) population-based BRCA testing is acceptable, cost-effective and amplifies primary prevention for breast & ovarian cancer. However, data describing lifestyle impact are lacking. We report long-term results of population-based BRCA testing on lifestyle behaviour and cancer risk perception.<h4>Design</h4>Two-arm randomised controlled trials (ISRCTN73338115, GCaPPS): (a) population-screening (PS); (b) family history (FH)/clinical criteria testing.<h4>Setting</h4>North London AJ-population.<h4>Population/sample</h4>AJ women/men >18 years.<h4>Exclusions</h4>prior BRCA testing or first-degree relatives of BRCA-carriers.<h4>Methods</h4>Participants were recruited through self-referral. All participants received informed pre-test genetic counselling. The inte"],"journal":["BJOG : an international journal of obstetrics and gynaecology"],"pubmed_title":["Randomised trial of population-based BRCA testing in Ashkenazi Jews: long-term secondary lifestyle behavioural outcomes."],"pmcid":["PMC9796935"],"funding_grant_id":["GTCV","PT","MC_UU_00004/01"],"pubmed_authors":["Wardle J","Burnell M","Sanderson S","Legood R","Beller U","Sobocan M","Tomlinson I","Brady AF","Desai R","Loggenberg K","Jacobs I","Menon U","Gessler S","Gaba F","Dorkins H","Jacobs C","Side L","Wallis Y","Manchanda R"],"additional_accession":[]},"is_claimable":false,"name":"Randomised trial of population-based BRCA testing in Ashkenazi Jews: long-term secondary lifestyle behavioural outcomes.","description":"<h4>Objective</h4>Ashkenazi-Jewish (AJ) population-based BRCA testing is acceptable, cost-effective and amplifies primary prevention for breast & ovarian cancer. However, data describing lifestyle impact are lacking. We report long-term results of population-based BRCA testing on lifestyle behaviour and cancer risk perception.<h4>Design</h4>Two-arm randomised controlled trials (ISRCTN73338115, GCaPPS): (a) population-screening (PS); (b) family history (FH)/clinical criteria testing.<h4>Setting</h4>North London AJ-population.<h4>Population/sample</h4>AJ women/men >18 years.<h4>Exclusions</h4>prior BRCA testing or first-degree relatives of BRCA-carriers.<h4>Methods</h4>Participants were recruited through self-referral. All participants received informed pre-test genetic counselling. The inte","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-04T10:59:00.284Z","creation":"2025-04-04T10:59:00.284Z"},"accession":"S-EPMC9796935","cross_references":{"pubmed":["35781768"],"doi":["10.1111/1471-0528.17253"]}}