biostudies-literatureUnknown12Martin H<h4>Background</h4>The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible treatment of childhood pneumonia for the improvement of current pneumonia case management guidelines.<h4>Methods</h4>Using data from a published systematic review and expert knowledge, we identified studies meeting our eligibility criteria and invited investigators to share individual-level patient data. We collected data on demographic informatJournal of global health04075https://www.ebi.ac.uk/biostudies/studies/S-EPMC9798037biostudies-literatureAssembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: Methodology and applications.PMC9798037Banajeh SPatel ARasmussen ZMino GMwansambo CZaman SMAneja SRuvinsky ROCutland CBhutta ZANunes MCWang JMartin HAsghar RBrooks ARussomando GMadhi SAParanhos-Baccala GHibberd PLKartasasmita CBSaha SKRakoto-Andrianarivelo MSinghi SIqbal IPicot VSJeena PStrand TAWorld Health Organization Pneumonia Research Partnership to Assess WHO Recommendation (PREPARE) study groupThamthitiwat SMathew JLHazir TNisar YBLucero MPape JWFalconer JEchavarria MLibster RWadhwa NChisaka NAddo-Yobo EGregory CJThea DMNair HBavdekar AClara AWO'Grady KFLufesi NLozano JMSantosham MSylla MTurner CNguyen NTVColbourn TArroyo LMNeuman MIGentile ABasnet SBhandari NChou MSadruddin SBari AChadha MHooli SVanhems PGessner BRouzier VQazi SAKing CMcCollum EDBhatnagar SCampbell HSoofi SMaulen-Radovan IHirve SMacLeod WBAwasthi SD'Acremont VLodha RNymadawa PfalseAssembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm: Methodology and applications.<h4>Background</h4>The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible treatment of childhood pneumonia for the improvement of current pneumonia case management guidelines.<h4>Methods</h4>Using data from a published systematic review and expert knowledge, we identified studies meeting our eligibility criteria and invited investigators to share individual-level patient data. We collected data on demographic informat2022-01-01T00:00:00Z2022 Dec2025-04-04T19:09:00.299Z2025-04-04T19:09:00.299ZS-EPMC97980373657941710.7189/jogh.12.04075