biostudies-literatureUnknown24(1)Verlaat CW<h4>Objectives</h4>Some patients with a low predicted mortality risk in the PICU die. The contribution of adverse events to mortality in this group is unknown. The aim of this study was to estimate the occurrence of adverse events in low-risk nonsurvivors (LN), compared with low-risk survivors (LS) and high-risk PICU survivors and nonsurvivors, and the contribution of adverse events to mortality.<h4>Design</h4>Case control study. Admissions were selected from the national Dutch PICU registry, containing 53,789 PICU admissions between 2006 and 2017, in seven PICUs. PICU admissions were stratified into four groups, based on mortality risk (low/high) and outcome (death/survival). Random samples were selected from the four groups. Cases were "LN." Control groups were as follows: "LS," "high-riPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies4-16https://www.ebi.ac.uk/biostudies/studies/S-EPMC9799043biostudies-literatureAdverse Events in Pediatric Critical Care Nonsurvivors With a Low Predicted Mortality Risk: A Multicenter Case Control Study.PMC9799043Klein Rvan Waardenburg DPICE registry (Pediatric Intensive Care Evaluation)/SKIC (Dutch Collaborative PICU Research Network)Kuiper JWvan der Hoeven Jvan Heerde MVerlaat CWTimmers BZegers MKneyber MHazelzet JARiedijk MLemson JfalseAdverse Events in Pediatric Critical Care Nonsurvivors With a Low Predicted Mortality Risk: A Multicenter Case Control Study.<h4>Objectives</h4>Some patients with a low predicted mortality risk in the PICU die. The contribution of adverse events to mortality in this group is unknown. The aim of this study was to estimate the occurrence of adverse events in low-risk nonsurvivors (LN), compared with low-risk survivors (LS) and high-risk PICU survivors and nonsurvivors, and the contribution of adverse events to mortality.<h4>Design</h4>Case control study. Admissions were selected from the national Dutch PICU registry, containing 53,789 PICU admissions between 2006 and 2017, in seven PICUs. PICU admissions were stratified into four groups, based on mortality risk (low/high) and outcome (death/survival). Random samples were selected from the four groups. Cases were "LN." Control groups were as follows: "LS," "high-ri2023-01-01T00:00:00Z2023 Jan2025-04-04T10:59:05.336Z2025-04-04T10:59:05.336ZS-EPMC97990433652101310.1097/PCC.0000000000003103