{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Vasquez PM"],"funding":["NIA NIH HHS","NHLBI NIH HHS","National Heart, Lung, and Blood Institute","NIMHD NIH HHS","National Institute on Minority Health and Health Disparities","National Institute on Aging"],"pagination":["e263-e278"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9799203"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["77(12)"],"pubmed_abstract":["<h4>Objectives</h4>Derive latent profiles of accelerometry-measured moderate-vigorous physical activity (MVPA) for Hispanic/Latino adults, examine associations between latent MVPA profiles and neurocognition, and describe profiles via self-reported MVPA.<h4>Methods</h4>Complex survey design methods were applied to cross-sectional data from 7,672 adults ages 45-74 years in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL; 2008-2011). MVPA was measured via hip-worn accelerometers. Latent profile analysis was applied to derive latent MVPA profiles (minutes/day of week). Neurocognition was assessed with the Brief-Spanish English Verbal Learning Test (B-SEVLT) Sum, B-SEVLT Recall, Controlled Oral Word Association Test (word fluency), and Digit Symbol Substitution (DSS) test. All tests were z-scored, and a global neurocognition score was generated by averaging across scores. Survey linear regression models were used to examine associations between latent MVPA profiles and neurocognitive measures. Self-reported MVPA domains were estimated (occupational, transportation, and recreational) for each latent profile.<h4>Results</h4>Four latent MVPA profiles from the overall adult target population (18-74 years) were derived and putatively labeled: No MVPA, low, moderate, and high. Only the high MVPA profile (compared to moderate) was associated with lower global neurocognition. Sensitivity analyses using latent MVPA profiles with only participants aged 45-74 years showed similar profiles, but no associations between latent MVPA profiles and neurocognition. The occupational MVPA domain led in all latent MVPA profiles.<h4>Discussion</h4>We found no consistent evidence to link accelerometry-measured MVPA profiles to neurocognitive function. Research to better characterize the role of high occupational MVPA in relation to neurocognition among Hispanic/Latino adults are needed."],"journal":["The journals of gerontology. Series B, Psychological sciences and social sciences"],"pubmed_title":["Accelerometer-Measured Latent Physical Activity Profiles and Neurocognition Among Middle-Aged and Older Hispanic/Latino Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)."],"pmcid":["PMC9799203"],"funding_grant_id":["R56 AG048642","N01 HC065233","K01 AG075353","L60 MD015551","S21 MD000103","P30 AG059299","5T32HL079891-13","R56AG048642","P30AG059299","T32 HL079891","N01 HC065236","75N92019D00012","N01 HC065237","N01 HC065234","N01 HC065235","R01AG048642"],"pubmed_authors":["Daviglus ML","Schneiderman N","Gallo LC","Singer RH","Diaz KM","Vasquez E","Evenson KR","Sotres-Alvarez D","Doza A","Zlatar ZZ","Tarraf W","Durazo-Arvizu RA","Vasquez PM","Khambaty T","Thyagarajan B","Chai A","Gonzalez HM","Estrella ML"],"additional_accession":[]},"is_claimable":false,"name":"Accelerometer-Measured Latent Physical Activity Profiles and Neurocognition Among Middle-Aged and Older Hispanic/Latino Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).","description":"<h4>Objectives</h4>Derive latent profiles of accelerometry-measured moderate-vigorous physical activity (MVPA) for Hispanic/Latino adults, examine associations between latent MVPA profiles and neurocognition, and describe profiles via self-reported MVPA.<h4>Methods</h4>Complex survey design methods were applied to cross-sectional data from 7,672 adults ages 45-74 years in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL; 2008-2011). MVPA was measured via hip-worn accelerometers. Latent profile analysis was applied to derive latent MVPA profiles (minutes/day of week). Neurocognition was assessed with the Brief-Spanish English Verbal Learning Test (B-SEVLT) Sum, B-SEVLT Recall, Controlled Oral Word Association Test (word fluency), and Digit Symbol Substitution (DSS) test. All tests were z-scored, and a global neurocognition score was generated by averaging across scores. Survey linear regression models were used to examine associations between latent MVPA profiles and neurocognitive measures. Self-reported MVPA domains were estimated (occupational, transportation, and recreational) for each latent profile.<h4>Results</h4>Four latent MVPA profiles from the overall adult target population (18-74 years) were derived and putatively labeled: No MVPA, low, moderate, and high. Only the high MVPA profile (compared to moderate) was associated with lower global neurocognition. Sensitivity analyses using latent MVPA profiles with only participants aged 45-74 years showed similar profiles, but no associations between latent MVPA profiles and neurocognition. The occupational MVPA domain led in all latent MVPA profiles.<h4>Discussion</h4>We found no consistent evidence to link accelerometry-measured MVPA profiles to neurocognitive function. Research to better characterize the role of high occupational MVPA in relation to neurocognition among Hispanic/Latino adults are needed.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-26T13:32:20.401Z","creation":"2025-04-06T14:14:27.083Z"},"accession":"S-EPMC9799203","cross_references":{"pubmed":["36219450"],"doi":["10.1093/geronb/gbac161"]}}