biostudies-literatureUnknown22(1)Liu Q<h4>Purpose</h4>To compare morphological changes in the anterior capsule of two intraocular lenses (IOLs) with different anterior edge designs 6 months after femtosecond laser-assisted capsulotomy surgery (FLACs).<h4>Methods</h4>This study included 168 eyes from168 patients undergoing FLACs. Group A included 74 eyes from 74 patients who had an Acrysof IQ Restor SN6AD3 IOL implantation with a flat anterior edge and Group B included 94 eyes of 94 patients with a TECNIS Multifocal ZMB00 IOL implantation and a "peak-like" anterior edge. All patients were followed up for 6 months. We assessed anterior capsule morphological changes including variation of anterior opening diameters and lens epithelial cell (LEC) proliferation in four directions, variation of anterior opening area, and the level oBMC ophthalmology515https://www.ebi.ac.uk/biostudies/studies/S-EPMC9801536biostudies-literatureEffects of intraocular lens anterior edge design on anterior capsule morphology changes following femtosecond laser-assisted capsulotomy.PMC9801536Liu JLiu QZhou GWang XZhang SYuan XfalseEffects of intraocular lens anterior edge design on anterior capsule morphology changes following femtosecond laser-assisted capsulotomy.<h4>Purpose</h4>To compare morphological changes in the anterior capsule of two intraocular lenses (IOLs) with different anterior edge designs 6 months after femtosecond laser-assisted capsulotomy surgery (FLACs).<h4>Methods</h4>This study included 168 eyes from168 patients undergoing FLACs. Group A included 74 eyes from 74 patients who had an Acrysof IQ Restor SN6AD3 IOL implantation with a flat anterior edge and Group B included 94 eyes of 94 patients with a TECNIS Multifocal ZMB00 IOL implantation and a "peak-like" anterior edge. All patients were followed up for 6 months. We assessed anterior capsule morphological changes including variation of anterior opening diameters and lens epithelial cell (LEC) proliferation in four directions, variation of anterior opening area, and the level o2022-01-01T00:00:00Z2022 Dec2025-04-21T15:23:32.637Z2025-02-19T03:30:51.589ZS-EPMC98015363658192510.1186/s12886-022-02751-x