biostudies-literatureKustiana BAFondation Schlumberger pour l’Education et la RechercheFondation Schlumberger pour l'Education et la RechercheCultural Affairs and Missions Sector, Ministry of Higher EducationEngineering and Physical Sciences Research Councile202202454https://www.ebi.ac.uk/biostudies/studies/S-EPMC9804281biostudies-literatureUnknown28(63)Herein, we report the B(C<sub>6</sub> F<sub>5</sub> )<sub>3</sub> -catalyzed E-selective isomerization of alkenes. The transition-metal-free method is applicable across a diverse array of readily accessible substrates, giving access to a broad range of synthetically useful products containing versatile stereodefined internal alkenes. The reaction mechanism was investigated by using synthetic and computational methods.Chemistry (Weinheim an der Bergstrasse, Germany)B(C<sub>6</sub> F<sub>5</sub> )<sub>3</sub> -Catalyzed E-Selective Isomerization of Alkenes.PMC9804281EP/L016443/1Melen RLElsherbeni SALinford-Wood TGGrayson MNKustiana BAMorrill LCfalseB(C<sub>6</sub> F<sub>5</sub> )<sub>3</sub> -Catalyzed E-Selective Isomerization of Alkenes.Herein, we report the B(C<sub>6</sub> F<sub>5</sub> )<sub>3</sub> -catalyzed E-selective isomerization of alkenes. The transition-metal-free method is applicable across a diverse array of readily accessible substrates, giving access to a broad range of synthetically useful products containing versatile stereodefined internal alkenes. The reaction mechanism was investigated by using synthetic and computational methods.2022-01-01T00:00:00Z2022 Nov2025-04-05T12:09:46.541Z2025-04-05T12:09:46.541ZS-EPMC98042813594308210.1002/chem.202202454