{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rodiah I"],"funding":["Bundesministerium für Bildung und Forschung","European Research Council","Initiative and Networking Fund of the Helmholtz Association","Helmholtz-Zentrum für Infektionsforschung GmbH (HZI)","Standing Conference of the Ministers of Education and Cultural Affairs","Standing Conference of the Ministers of Education and Cultural Affairs (KMK)"],"pagination":["39-58"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9807433"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["38(1)"],"pubmed_abstract":["Current estimates of pandemic SARS-CoV-2 spread in Germany using infectious disease models often do not use age-specific infection parameters and are not always based on age-specific contact matrices of the population. They also do usually not include setting- or pandemic phase-based information from epidemiological studies of reported cases and do not account for age-specific underdetection of reported cases. Here, we report likely pandemic spread using an age-structured model to understand the age- and setting-specific contribution of contacts to transmission during different phases of the COVID-19 pandemic in Germany. We developed a deterministic SEIRS model using a pre-pandemic contact matrix. The model was optimized to fit age-specific SARS-CoV-2 incidences reported by the German Nati"],"journal":["European journal of epidemiology"],"pubmed_title":["Age-specific contribution of contacts to transmission of SARS-CoV-2 in Germany."],"pmcid":["PMC9807433"],"funding_grant_id":["101003480 (Project CORESMA)","FKZ: 01KX2021 (Project COVIM: \"NaFOUniMedCovid19\")","FKZ: 01KX2021 (Project COVIM: “NaFOUniMedCovid19”)","Project COVID-SCHULEN"],"pubmed_authors":["Kuhlmann A","Vanella P","Bock W","Lange B","Jaeger VK","Harries M","Karch A","Rodiah I","Krause G"],"additional_accession":[]},"is_claimable":false,"name":"Age-specific contribution of contacts to transmission of SARS-CoV-2 in Germany.","description":"Current estimates of pandemic SARS-CoV-2 spread in Germany using infectious disease models often do not use age-specific infection parameters and are not always based on age-specific contact matrices of the population. They also do usually not include setting- or pandemic phase-based information from epidemiological studies of reported cases and do not account for age-specific underdetection of reported cases. Here, we report likely pandemic spread using an age-structured model to understand the age- and setting-specific contribution of contacts to transmission during different phases of the COVID-19 pandemic in Germany. We developed a deterministic SEIRS model using a pre-pandemic contact matrix. The model was optimized to fit age-specific SARS-CoV-2 incidences reported by the German Nati","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-03-18T13:49:58.149Z","creation":"2024-11-21T07:53:34.844Z"},"accession":"S-EPMC9807433","cross_references":{"pubmed":["36593336"],"doi":["10.1007/s10654-022-00938-6"]}}