{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["3(1)"],"submitter":["Zhang JQ"],"pubmed_abstract":["For over half a century, thousands of tons of triphenylphosphine oxide Ph<sub>3</sub>P(O) have been produced every year from the chemical industries as a useless chemical waste. Here we disclose efficient transformations of Ph<sub>3</sub>P(O) with cheap resource-abundant metallic sodium finely dispersed in paraffin oil. Ph<sub>3</sub>P(O) can be easily and selectively transformed to three reactive organophosphorus intermediates-sodium diphenylphosphinite, sodium 5H-benzo[b]phosphindol-5-olate and sodium benzo[b]phosphindol-5-ide-that efficiently give the corresponding functional organophosphorus compounds in good yields. These functional organophosphorus compounds are difficult to prepare but highly industrially useful compounds. This may allow Ph<sub>3</sub>P(O) to be used as a precious s"],"journal":["Communications chemistry"],"pagination":["1"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9812262"],"repository":["biostudies-literature"],"pubmed_title":["Conversion of triphenylphosphine oxide to organophosphorus via selective cleavage of C-P, O-P, and C-H bonds with sodium."],"pmcid":["PMC9812262"],"pubmed_authors":["Huang T","Shinohara H","Han LB","Zhang JQ","Ye J","Fujino H"],"additional_accession":[]},"is_claimable":false,"name":"Conversion of triphenylphosphine oxide to organophosphorus via selective cleavage of C-P, O-P, and C-H bonds with sodium.","description":"For over half a century, thousands of tons of triphenylphosphine oxide Ph<sub>3</sub>P(O) have been produced every year from the chemical industries as a useless chemical waste. Here we disclose efficient transformations of Ph<sub>3</sub>P(O) with cheap resource-abundant metallic sodium finely dispersed in paraffin oil. Ph<sub>3</sub>P(O) can be easily and selectively transformed to three reactive organophosphorus intermediates-sodium diphenylphosphinite, sodium 5H-benzo[b]phosphindol-5-olate and sodium benzo[b]phosphindol-5-ide-that efficiently give the corresponding functional organophosphorus compounds in good yields. These functional organophosphorus compounds are difficult to prepare but highly industrially useful compounds. This may allow Ph<sub>3</sub>P(O) to be used as a precious s","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jan","modification":"2026-03-27T15:36:19.635Z","creation":"2025-04-05T21:40:51.638Z"},"accession":"S-EPMC9812262","cross_references":{"pubmed":["36703346"],"doi":["10.1038/s42004-019-0249-6"]}}