{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Ai L"],"pubmed_abstract":["Botanical pesticides are one of the sources of third-generation pesticides, which have received much attention at home and abroad in recent years due to their degradable and pollution-free advantages in nature. This article explored a concise approach toward synthesizing a series of novel L-pyroglutamic acid analogues from L-hydroxyproline. Furthermore, bioassay studies of these sulfonyl ester derivatives against <i>Pyricularia oryzae</i>, <i>Fusarium graminearum</i>, <i>Alternaria brassicae</i>, <i>Valsa mali</i>, and <i>Alternaria alternariae</i> showed moderate antifungal activity. For instance, <b>C08a</b> and <b>C08l</b> provide potential lead agents for controlling <i>Fusarium graminearum</i> because of their inhibitory activity."],"journal":["Frontiers in plant science"],"pagination":["1102411"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9815151"],"repository":["biostudies-literature"],"pubmed_title":["Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues."],"pmcid":["PMC9815151"],"pubmed_authors":["Li Y","Fu S","Huang J","Huang W","Zuo M","Chen Y","Ai L","Jin Z"],"additional_accession":[]},"is_claimable":false,"name":"Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues.","description":"Botanical pesticides are one of the sources of third-generation pesticides, which have received much attention at home and abroad in recent years due to their degradable and pollution-free advantages in nature. This article explored a concise approach toward synthesizing a series of novel L-pyroglutamic acid analogues from L-hydroxyproline. Furthermore, bioassay studies of these sulfonyl ester derivatives against <i>Pyricularia oryzae</i>, <i>Fusarium graminearum</i>, <i>Alternaria brassicae</i>, <i>Valsa mali</i>, and <i>Alternaria alternariae</i> showed moderate antifungal activity. For instance, <b>C08a</b> and <b>C08l</b> provide potential lead agents for controlling <i>Fusarium graminearum</i> because of their inhibitory activity.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-29T20:15:48.009Z","creation":"2025-04-04T13:52:48.919Z"},"accession":"S-EPMC9815151","cross_references":{"pubmed":["36618642"],"doi":["10.3389/fpls.2022.1102411"]}}