{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ni XB"],"funding":["National Natural Science Foundation of China"],"pagination":["162-173"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9816062"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(1)"],"pubmed_abstract":["The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate"],"journal":["Nature microbiology"],"pubmed_title":["Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes."],"pmcid":["PMC9816062"],"funding_grant_id":["81621005","31922087","82103897"],"pubmed_authors":["Zhou YH","Qin Q","Wu YQ","Zhang J","Cao WC","Shen SJ","Du CH","Tick Genome and Microbiome Consortium (TIGMIC)","Shao HZ","Huang EJ","Ding SJ","Shum MH","Pan YS","Lam TT","Zhao L","Ruan XD","Jia N","Wang Q","Zhu JG","Que TC","Liu JY","Wang X","Zhan L","Han XH","Guo WB","Xia LY","Chang QC","Ye RZ","Jiang JF","Chen QQ","Shi WQ","Cui XM","Sun Y","Zhu DY","Gong CW","Ni XB","Zhang MZ","Qu JL","Liu GY","Du LF","Ma J","Ma K","Oong XY","Wang CC","Li LJ"],"additional_accession":[]},"is_claimable":false,"name":"Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes.","description":"The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-05-29T21:09:03.401Z","creation":"2024-12-04T02:35:32.522Z"},"accession":"S-EPMC9816062","cross_references":{"pubmed":["36604510"],"doi":["10.1038/s41564-022-01275-w"]}}