biostudies-literatureAkram MJScience and Technology Innovation Project of "Chengdu-Chongqing Economic Circle"National Key R&amp;D Program of ChinaChongqing Innovation Support Program for Returned Overseas Chinese ScholarsNational Natural Science Foundation of ChinaChongqing Science Fund for Distinguished Young ScholarsChongqing High-end Young Investigator Project66https://www.ebi.ac.uk/biostudies/studies/S-EPMC9821144biostudies-literatureUnknown12(1)The mortality of stroke increases on weekends and during off-hour periods. We investigated the effect of off-hour admission on the outcomes of intracerebral hemorrhage (ICH) patients. We retrospectively analyzed a prospective cohort of ICH patients, admitted between January 2017 and December 2019 at the First Affiliated Hospital of Chongqing Medical University. Acute ICH within 72 h after onset with a baseline computed tomography and 3-month follow-up were included in our study. Multivariable logistic regression analysis was performed for calculating the odds ratios (OR) and 95% confidence interval (CI) for the outcome measurements. Of the 656 participants, 318 (48.5%) were admitted during on-hours, whereas 338 (51.5%) were admitted during off-hours. Patients with a poor outcome had a larger median baseline hematoma volume, of 27 mL (interquartile range 11.1-53.2 mL), and a lower median time from onset to imaging, of 2.8 h (interquartile range 1.4-9.6 h). Off-hour admission was significantly associated with a poor functional outcome at 3 months, after adjusting for cofounders (adjusted OR 2.17, 95% CI 1.35-3.47; <i>p</i> = 0.001). We found that patients admitted during off-hours had a higher risk of poor functional outcomes at 3 months than those admitted during working hours.Journal of clinical medicineOff-Hour Admission Is Associated with Poor Outcome in Patients with Intracerebral Hemorrhage.PMC9821144KJCXZD20200192019GDRC00582071337cstc2021jcyj-jqX00292018YFC1312200 and 2018YFC1312203cx2020002Akram MJYin HLi ZZhao LPu MLv XDeng LLi QYang TChen CWu XfalseOff-Hour Admission Is Associated with Poor Outcome in Patients with Intracerebral Hemorrhage.The mortality of stroke increases on weekends and during off-hour periods. We investigated the effect of off-hour admission on the outcomes of intracerebral hemorrhage (ICH) patients. We retrospectively analyzed a prospective cohort of ICH patients, admitted between January 2017 and December 2019 at the First Affiliated Hospital of Chongqing Medical University. Acute ICH within 72 h after onset with a baseline computed tomography and 3-month follow-up were included in our study. Multivariable logistic regression analysis was performed for calculating the odds ratios (OR) and 95% confidence interval (CI) for the outcome measurements. Of the 656 participants, 318 (48.5%) were admitted during on-hours, whereas 338 (51.5%) were admitted during off-hours. Patients with a poor outcome had a larger median baseline hematoma volume, of 27 mL (interquartile range 11.1-53.2 mL), and a lower median time from onset to imaging, of 2.8 h (interquartile range 1.4-9.6 h). Off-hour admission was significantly associated with a poor functional outcome at 3 months, after adjusting for cofounders (adjusted OR 2.17, 95% CI 1.35-3.47; <i>p</i> = 0.001). We found that patients admitted during off-hours had a higher risk of poor functional outcomes at 3 months than those admitted during working hours.2022-01-01T00:00:00Z2022 Dec2025-04-21T16:16:47.114Z2025-04-21T16:16:47.114ZS-EPMC98211443661486710.3390/jcm12010066