{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Anchesi I"],"funding":["Ministero della Salute"],"pagination":["193"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9823669"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["Cannabigerol (CBG) is a non-psychoactive phytocannabinoid present in the <i>Cannabis sativa</i> L. plant. In our study, CBG at the concentration of 10 µM was used to treat NSC-34 motor neuron-like cells. The aim of the study was to evaluate the effects of CBG on NSC-34 cells, using next-generation sequencing (NGS) technology. Analysis showed the activation of the WNT/planar cell polarity (PCP) pathway and Ephrin-Eph signaling. The results revealed that CBG increases the expression of genes associated with the onset process of cytoskeletal remodeling and axon guidance."],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["Cannabigerol Activates Cytoskeletal Remodeling via Wnt/PCP in NSC-34: An In Vitro Transcriptional Study."],"pmcid":["PMC9823669"],"funding_grant_id":["Current Research Funds 2022"],"pubmed_authors":["Anchesi I","Salamone S","Gugliandolo A","Pollastro F","Mazzon E","Chiricosta L","Betto F"],"additional_accession":[]},"is_claimable":false,"name":"Cannabigerol Activates Cytoskeletal Remodeling via Wnt/PCP in NSC-34: An In Vitro Transcriptional Study.","description":"Cannabigerol (CBG) is a non-psychoactive phytocannabinoid present in the <i>Cannabis sativa</i> L. plant. In our study, CBG at the concentration of 10 µM was used to treat NSC-34 motor neuron-like cells. The aim of the study was to evaluate the effects of CBG on NSC-34 cells, using next-generation sequencing (NGS) technology. Analysis showed the activation of the WNT/planar cell polarity (PCP) pathway and Ephrin-Eph signaling. The results revealed that CBG increases the expression of genes associated with the onset process of cytoskeletal remodeling and axon guidance.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-21T16:19:33.023Z","creation":"2024-11-08T22:05:34.056Z"},"accession":"S-EPMC9823669","cross_references":{"pubmed":["36616322"],"doi":["10.3390/plants12010193"]}}