{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yu JL"],"funding":["Biotechnological and Biological Research Council","Cancer Research UK","111 Project","National Natural Science Foundation of China","Biotechnology and Biological Sciences Research Council","Sichuan Science and Technology Program"],"pagination":["D593-D602"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9825548"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["51(D1)"],"pubmed_abstract":["Metalloenzymes are attractive research targets in fields of chemistry, biology, and medicine. Given that metalloenzymes can manifest conservation of metal-coordination and ligand binding modes, the excavation and expansion of metalloenzyme-specific knowledge is of interest in bridging metalloenzyme-related fields. Building on our previous metalloenzyme-ligand association database, MeLAD, we have expanded the scope of metalloenzyme-specific knowledge and services, by forming a versatile platform, termed the Metalloenzyme Data Bank and Analysis (MeDBA). The MeDBA provides: (i) manual curation of metalloenzymes into different categories, that this M-I, M-II and M-III; (ii) comprehensive information on metalloenzyme activities, expression profiles, family and disease links; (iii) structural in"],"journal":["Nucleic acids research"],"pubmed_title":["MeDBA: the Metalloenzyme Data Bank and Analysis platform."],"pmcid":["PMC9825548"],"funding_grant_id":["2022YFH0027","BB/V003291/1","82073698","BB/V001892/1","B18035","82122065","81874291"],"pubmed_authors":["Li GB","Dai QQ","Zhou C","Wu S","Yu JL","Schofield CJ"],"additional_accession":[]},"is_claimable":false,"name":"MeDBA: the Metalloenzyme Data Bank and Analysis platform.","description":"Metalloenzymes are attractive research targets in fields of chemistry, biology, and medicine. Given that metalloenzymes can manifest conservation of metal-coordination and ligand binding modes, the excavation and expansion of metalloenzyme-specific knowledge is of interest in bridging metalloenzyme-related fields. Building on our previous metalloenzyme-ligand association database, MeLAD, we have expanded the scope of metalloenzyme-specific knowledge and services, by forming a versatile platform, termed the Metalloenzyme Data Bank and Analysis (MeDBA). The MeDBA provides: (i) manual curation of metalloenzymes into different categories, that this M-I, M-II and M-III; (ii) comprehensive information on metalloenzyme activities, expression profiles, family and disease links; (iii) structural in","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-05-27T11:04:30.904Z","creation":"2026-04-08T01:37:47.343Z"},"accession":"S-EPMC9825548","cross_references":{"pubmed":["36243971"],"doi":["10.1093/nar/gkac860"]}}