biostudies-literatureUnknown74Statlender L<h4>Purpose</h4>Vasopressin has become an important vasopressor drug while treating a critically ill patient to maintain adequate mean arterial pressure. Diabetes insipidus (DI) is a rare syndrome characterized by the excretion of a large volume of diluted urine, inappropriate for water homeostasis. We noticed that several COVID19 patients developed excessive polyuria suggestive of DI, with a concomitant plasma sodium-level increase and/or low urine osmolality. We noticed a temporal relationship between vasopressin treatment cessation and polyuria periods. We reviewed those cases to better describe this phenomenon.<h4>Methods</h4>We retrospectively collected COVID19 ECMO patients' (from July 6, 2020, to November 30, 2021) data from the electronic medical records. By examining urine output,Journal of critical care154211https://www.ebi.ac.uk/biostudies/studies/S-EPMC9828890biostudies-literatureTransient diabetes insipidus in critically ill COVID19 patients.PMC9828890Singer PStatlender LKagan IBendavid IKaptzon SHellerman MFishman GGorfil DfalseTransient diabetes insipidus in critically ill COVID19 patients.<h4>Purpose</h4>Vasopressin has become an important vasopressor drug while treating a critically ill patient to maintain adequate mean arterial pressure. Diabetes insipidus (DI) is a rare syndrome characterized by the excretion of a large volume of diluted urine, inappropriate for water homeostasis. We noticed that several COVID19 patients developed excessive polyuria suggestive of DI, with a concomitant plasma sodium-level increase and/or low urine osmolality. We noticed a temporal relationship between vasopressin treatment cessation and polyuria periods. We reviewed those cases to better describe this phenomenon.<h4>Methods</h4>We retrospectively collected COVID19 ECMO patients' (from July 6, 2020, to November 30, 2021) data from the electronic medical records. By examining urine output,2023-01-01T00:00:00Z2023 Jan2025-04-22T19:57:51.302Z2025-04-06T02:55:31.337ZS-EPMC98288903663085910.1016/j.jcrc.2022.154211