biostudies-literatureWang YXNIEHS NIH HHSFoundation for the National Institutes of HealthNHLBI NIH HHSNCI NIH HHSNational Institutes of Health100344https://www.ebi.ac.uk/biostudies/studies/S-EPMC9830740biostudies-literatureUnknown15<h4>Background</h4>Weight at birth has been associated with the development of various adult diseases, but its association with mortality remains unclear.<h4>Methods</h4>We included 22,389 men from the Health Professionals Follow-up Study (1994-2018) and 162,231 women from the Nurses' Health Study (1992-2018) and the Nurses' Health Study II (1991-2019). The hazard ratios (HRs) of mortality according to birth weight were estimated by Cox proportional hazards regression models with adjustment for potential confounders.<h4>Findings</h4>Compared to women reporting a birth weight of 3.16-3.82 kg, the pooled HRs for all-cause mortality were 1.13 (95% CI, 1.08 to 1.17), 0.99 (95% CI, 0.96 to 1.02), 1.04 (95% CI, 1.00 to 1.08), and 1.03 (95% CI, 0.96 to 1.10), respectively, for women with a birth Lancet regional health. AmericasBirth weight and long-term risk of mortality among US men and women: Results from three prospective cohort studies.PMC9830740R01 HL034594R01 HL035464U01 CA167552U01 HL145386R01 CA049449P01 CA087969U01 CA176726R01 CA067262R24 ES028521R01 HL088521UM1 CA186107Rich-Edwards JWLi YManson JEChavarro JEWang YXFlorio AADing MWang LfalseBirth weight and long-term risk of mortality among US men and women: Results from three prospective cohort studies.<h4>Background</h4>Weight at birth has been associated with the development of various adult diseases, but its association with mortality remains unclear.<h4>Methods</h4>We included 22,389 men from the Health Professionals Follow-up Study (1994-2018) and 162,231 women from the Nurses' Health Study (1992-2018) and the Nurses' Health Study II (1991-2019). The hazard ratios (HRs) of mortality according to birth weight were estimated by Cox proportional hazards regression models with adjustment for potential confounders.<h4>Findings</h4>Compared to women reporting a birth weight of 3.16-3.82 kg, the pooled HRs for all-cause mortality were 1.13 (95% CI, 1.08 to 1.17), 0.99 (95% CI, 0.96 to 1.02), 1.04 (95% CI, 1.00 to 1.08), and 1.03 (95% CI, 0.96 to 1.10), respectively, for women with a birth 2022-01-01T00:00:00Z2022 Nov2026-03-17T15:42:27.25Z2025-04-07T09:16:04.448ZS-EPMC98307403663204810.1016/j.lana.2022.100344