biostudies-literatureZhang YDepartment of Science and Technology of Sichuan Province5https://www.ebi.ac.uk/biostudies/studies/S-EPMC9830815biostudies-literatureUnknown23(1)<h4>Background</h4>The effects of body mass index (BMI) in patients with rectal cancer have been poorly studied and are still controversial. In this study, we aimed to assess the effect of BMI on the long-term outcome in patients with rectal cancer after radical surgery.<h4>Materials and methods</h4>Between April 2012 and December 2020, patients who received total mesorectal excision (TME) surgery were enrolled in the study. Patients were divided into four groups according to BMI level. Kaplan-Meier survival curves with log-rank tests were used to analyze overall survival (OS), Disease-free survival (DFS), local recurrence-free survival and distant metastasis-free survival. Univariate and multivariate analyses were performed to identify the risk factors associated with the long-term outcomBMC gastroenterologyThe effect of BMI on long-term outcome in patients with rectal cancer and establishment of a nomogram prediction model.PMC98308152019YFS0375Yang XWei MZhang YWang ZZhuang ZDeng XMeng WfalseThe effect of BMI on long-term outcome in patients with rectal cancer and establishment of a nomogram prediction model.<h4>Background</h4>The effects of body mass index (BMI) in patients with rectal cancer have been poorly studied and are still controversial. In this study, we aimed to assess the effect of BMI on the long-term outcome in patients with rectal cancer after radical surgery.<h4>Materials and methods</h4>Between April 2012 and December 2020, patients who received total mesorectal excision (TME) surgery were enrolled in the study. Patients were divided into four groups according to BMI level. Kaplan-Meier survival curves with log-rank tests were used to analyze overall survival (OS), Disease-free survival (DFS), local recurrence-free survival and distant metastasis-free survival. Univariate and multivariate analyses were performed to identify the risk factors associated with the long-term outcom2023-01-01T00:00:00Z2023 Jan2025-04-26T05:58:13.29Z2024-11-06T15:28:23.9ZS-EPMC98308153662439410.1186/s12876-023-02638-1