biostudies-literatureUnknown8(1)Lorente AA new selective fluorogenic chemosensor for Hg²⁺, which combines a calixarene derivative with a BODIPY core as a fluorescent reporter, is described. The remarkable change in its fluorogenic properties in DMSO and CHCl₃ has been analyzed. A study of its spectral properties on dilution, along with molecular modeling studies, allowed us to explain that this behavior involves the formation of a J-dimer, as well as how the sensing mechanism of Hg²⁺ proceeds.ACS omega819-828https://www.ebi.ac.uk/biostudies/studies/S-EPMC9835786biostudies-literatureUnconventional OFF-ON Response of a Mono(calix[4]arene)-Substituted BODIPY Sensor for Hg²⁺ through Dimerization Reversion.PMC9835786Gil SSaez JACostero AMJaque PRodriguez-Lavado JLorente AOchoa ARodriguez-Nuevalos SfalseUnconventional OFF-ON Response of a Mono(calix[4]arene)-Substituted BODIPY Sensor for Hg²⁺ through Dimerization Reversion.A new selective fluorogenic chemosensor for Hg²⁺, which combines a calixarene derivative with a BODIPY core as a fluorescent reporter, is described. The remarkable change in its fluorogenic properties in DMSO and CHCl₃ has been analyzed. A study of its spectral properties on dilution, along with molecular modeling studies, allowed us to explain that this behavior involves the formation of a J-dimer, as well as how the sensing mechanism of Hg²⁺ proceeds.2023-01-01T00:00:00Z2023 Jan2025-04-04T08:24:57.545Z2025-04-04T08:24:57.545ZS-EPMC98357863664345410.1021/acsomega.2c06161