{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["408(1)"],"submitter":["Kroh A"],"funding":["Ethicon","RWTH Aachen University"],"pubmed_abstract":["<h4>Study design</h4>A randomized, controlled, prospective multicenter clinical trial with a parallel group design was initiated in eight surgical centers to compare a large-pore polypropylene mesh (Ultrapro<sup>®</sup>) to a small-pore polypropylene mesh (Premilene<sup>®</sup>) within a standardized retromuscular meshplasty for incisional hernia repair.<h4>Methods</h4>Between 2004 and 2006, patients with a fascial defect with a minimum diameter of 4 cm after vertical midline laparotomy were recruited for the trial. Patients underwent retromuscular meshplasty with either a large-pore or a small-pore mesh to identify the superiority of the large-pore mesh. Follow-up visits were scheduled at 5 and 21 days and 4, 12, and 24 months after surgery. A clinical examination, a modified short form 3"],"journal":["Langenbeck's archives of surgery"],"pagination":["22"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9836964"],"repository":["biostudies-literature"],"pubmed_title":["No difference in outcomes between large- and small-pore meshes in a prospective, randomized, multicenter trial investigating open retromuscular meshplasty for incisional hernia repair."],"pmcid":["PMC9836964"],"pubmed_authors":["Zufacher M","Kroh A","Eickhoff R","Heise D","Ulmer F","Conze J","Helmedag M","Hilgers RD","Binnebosel M","Neumann UP"],"additional_accession":[]},"is_claimable":false,"name":"No difference in outcomes between large- and small-pore meshes in a prospective, randomized, multicenter trial investigating open retromuscular meshplasty for incisional hernia repair.","description":"<h4>Study design</h4>A randomized, controlled, prospective multicenter clinical trial with a parallel group design was initiated in eight surgical centers to compare a large-pore polypropylene mesh (Ultrapro<sup>®</sup>) to a small-pore polypropylene mesh (Premilene<sup>®</sup>) within a standardized retromuscular meshplasty for incisional hernia repair.<h4>Methods</h4>Between 2004 and 2006, patients with a fascial defect with a minimum diameter of 4 cm after vertical midline laparotomy were recruited for the trial. Patients underwent retromuscular meshplasty with either a large-pore or a small-pore mesh to identify the superiority of the large-pore mesh. Follow-up visits were scheduled at 5 and 21 days and 4, 12, and 24 months after surgery. A clinical examination, a modified short form 3","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-18T16:13:09.872Z","creation":"2025-04-07T03:17:46.849Z"},"accession":"S-EPMC9836964","cross_references":{"pubmed":["36635466"],"doi":["10.1007/s00423-022-02751-x"]}}