{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["36(1)"],"submitter":["Ramot Y"],"pubmed_abstract":["Laser resurfacing may be accompanied by unwanted side effects. The micro coring technology, designed to remove small skin columns, was developed to avoid the thermal injury associated with lasers. However, very limited data are available on its pre-clinical efficacy and safety. The novel robotic, fractional micro-coring device, Aime<sup>TM</sup>, was tested on four pigs, each treated in 12 sites, at 6 time-points, over the course of 28 days. Macroscopic and microscopic evaluation was performed at each of the 6 time-points during the 28-day follow-up. Macroscopically, treatment resulted in erythema and mild edema that quickly resolved. Microscopically, there was progressive re-coverage of the tested sites with complete, well differentiated, newly formed epidermis, associated with efficient "],"journal":["Journal of toxicologic pathology"],"pagination":["11-19"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9837470"],"repository":["biostudies-literature"],"pubmed_title":["Safety and efficacy of a novel robotic, fractional micro-coring device in a swine model."],"pmcid":["PMC9837470"],"pubmed_authors":["Vazana U","Ramot Y","Cacical O","Nyska A"],"additional_accession":[]},"is_claimable":false,"name":"Safety and efficacy of a novel robotic, fractional micro-coring device in a swine model.","description":"Laser resurfacing may be accompanied by unwanted side effects. The micro coring technology, designed to remove small skin columns, was developed to avoid the thermal injury associated with lasers. However, very limited data are available on its pre-clinical efficacy and safety. The novel robotic, fractional micro-coring device, Aime<sup>TM</sup>, was tested on four pigs, each treated in 12 sites, at 6 time-points, over the course of 28 days. Macroscopic and microscopic evaluation was performed at each of the 6 time-points during the 28-day follow-up. Macroscopically, treatment resulted in erythema and mild edema that quickly resolved. Microscopically, there was progressive re-coverage of the tested sites with complete, well differentiated, newly formed epidermis, associated with efficient ","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-04T14:27:27.531Z","creation":"2025-04-04T14:27:27.531Z"},"accession":"S-EPMC9837470","cross_references":{"pubmed":["36683728"],"doi":["10.1293/tox.2022-0079"]}}