{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bhatia NK"],"funding":["NHLBI NIH HHS"],"pagination":["e010502"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9839337"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(6)"],"pubmed_abstract":["<h4>Background</h4>Surgical ablation for atrial fibrillation (AF) can be effective, yet has mixed results. It is unclear which endocardial lesions delivered as part of hybrid therapy' will best augment surgical lesion sets in individual patients. We addressed this question by systematically mapping AF endocardially after surgical ablation and relating findings to early recurrence, then performing tailored endocardial ablation as part of hybrid therapy.<h4>Methods</h4>We studied 81 consecutive patients undergoing epicardial surgical ablation (stage 1 hybrid), of whom 64 proceeded to endocardial catheter mapping and ablation (stage 2). Stage 2 comprised high-density mapping of pulmonary vein (PV) or posterior wall (PW) reconnections, low-voltage zones (LVZs), and potential localized AF drive"],"journal":["Circulation. Arrhythmia and electrophysiology"],"pubmed_title":["Mapping Atrial Fibrillation After Surgical Therapy to Guide Endocardial Ablation."],"pmcid":["PMC9839337"],"funding_grant_id":["R01 HL083359","R01 HL149134"],"pubmed_authors":["Narayan SM","Wang PJ","Kapoor R","Rogers AJ","Badhwar N","Bhatia NK","Shah RL","Brodt C","Lee AM","Deb B","Pong T"],"additional_accession":[]},"is_claimable":false,"name":"Mapping Atrial Fibrillation After Surgical Therapy to Guide Endocardial Ablation.","description":"<h4>Background</h4>Surgical ablation for atrial fibrillation (AF) can be effective, yet has mixed results. It is unclear which endocardial lesions delivered as part of hybrid therapy' will best augment surgical lesion sets in individual patients. We addressed this question by systematically mapping AF endocardially after surgical ablation and relating findings to early recurrence, then performing tailored endocardial ablation as part of hybrid therapy.<h4>Methods</h4>We studied 81 consecutive patients undergoing epicardial surgical ablation (stage 1 hybrid), of whom 64 proceeded to endocardial catheter mapping and ablation (stage 2). Stage 2 comprised high-density mapping of pulmonary vein (PV) or posterior wall (PW) reconnections, low-voltage zones (LVZs), and potential localized AF drive","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jun","modification":"2025-04-04T08:06:25.753Z","creation":"2025-04-04T08:06:25.753Z"},"accession":"S-EPMC9839337","cross_references":{"pubmed":["35622437"],"doi":["10.1161/CIRCEP.121.010502","10.1161/circep.121.010502"]}}