biostudies-literatureSmith JLU.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and StrokeNIMH NIH HHSU.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS)NINDS NIH HHSEmory University Department of Radiology and Imaging Sciences29https://www.ebi.ac.uk/biostudies/studies/S-EPMC9840609biostudies-literatureUnknown10(1)Human vestibular processing involves distributed networks of cortical and subcortical regions which perform sensory and multimodal integrative functions. These functional hubs are also interconnected with areas subserving cognitive, affective, and body-representative domains. Analysis of these diverse components of the vestibular and vestibular-associated networks, and synthesis of their holistic functioning, is therefore vital to our understanding of the genesis of vestibular dysfunctions and aid treatment development. Novel neuroimaging methodologies, including functional and structural connectivity analyses, have provided important contributions in this area, but often require the use of atlases which are comprised of well-defined a priori regions of interest. Investigating vestibular dysfunction requires a more detailed atlas that encompasses cortical, subcortical, cerebellar, and brainstem regions. The present paper represents an effort to establish a compilation of existing, peer-reviewed brain atlases which collectively afford comprehensive coverage of these regions while explicitly focusing on vestibular substrates. It is expected that this compilation will be iteratively improved with additional contributions from researchers in the field.Scientific dataEagle-449: A volumetric, whole-brain compilation of brain atlases for vestibular functional MRI research.PMC9840609R01 NS119683R01NS119683U54 MH091657Smith JLGore RKAllen JWAhluwalia VfalseEagle-449: A volumetric, whole-brain compilation of brain atlases for vestibular functional MRI research.Human vestibular processing involves distributed networks of cortical and subcortical regions which perform sensory and multimodal integrative functions. These functional hubs are also interconnected with areas subserving cognitive, affective, and body-representative domains. Analysis of these diverse components of the vestibular and vestibular-associated networks, and synthesis of their holistic functioning, is therefore vital to our understanding of the genesis of vestibular dysfunctions and aid treatment development. Novel neuroimaging methodologies, including functional and structural connectivity analyses, have provided important contributions in this area, but often require the use of atlases which are comprised of well-defined a priori regions of interest. Investigating vestibular dysfunction requires a more detailed atlas that encompasses cortical, subcortical, cerebellar, and brainstem regions. The present paper represents an effort to establish a compilation of existing, peer-reviewed brain atlases which collectively afford comprehensive coverage of these regions while explicitly focusing on vestibular substrates. It is expected that this compilation will be iteratively improved with additional contributions from researchers in the field.2023-01-01T00:00:00Z2023 Jan2026-05-29T01:15:36.672Z2025-04-19T20:49:28.312ZS-EPMC98406093664151710.1038/s41597-023-01938-1