{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Filatava EJ"],"funding":["NINR NIH HHS","NIH HHS","U.S. Department of Health &amp; Human Services | National Institutes of Health"],"pagination":["60-67"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9840648"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["43(1)"],"pubmed_abstract":["<h4>Objective</h4>To compare pH of human milk types (mother's own milk (MOM), pasteurized donor human milk (PDHM), fortified MOM, and fortified PDHM) fed to preterm infants.<h4>Study design</h4>This observational study consisted of 63 mother-infant dyads < 34 weeks gestation. Human milk samples (n = 245), along with maternal factors, were collected for pH analysis. pH of MOM was analyzed over the course of lactation accounting for fortification status, postpartum day, and storage conditions.<h4>Results</h4>Mean pH of MOM was slightly acidic at 6.60 ± 0.28, which was significantly higher (p < 0.05) than other milk types. pH of MOM varied by fortification, postpartum day, and maternal vegetable/fiber intake. There was a significant interaction between fortification status and postpartum day; pH of MOM decreased over time, while pH of fortified MOM increased over time.<h4>Conclusion</h4>pH of human milk varied by type. pH of MOM was significantly associated with fortification status, postpartum day, and maternal vegetable/fiber intake."],"journal":["Journal of perinatology : official journal of the California Perinatal Association"],"pubmed_title":["Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads."],"pmcid":["PMC9840648"],"funding_grant_id":["R21NR017256","R21 NR017256"],"pubmed_authors":["Gregas M","Glynn R","Filatava EJ","Gregory KE","Overton NE","Shelly CE"],"additional_accession":[]},"is_claimable":false,"name":"Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads.","description":"<h4>Objective</h4>To compare pH of human milk types (mother's own milk (MOM), pasteurized donor human milk (PDHM), fortified MOM, and fortified PDHM) fed to preterm infants.<h4>Study design</h4>This observational study consisted of 63 mother-infant dyads < 34 weeks gestation. Human milk samples (n = 245), along with maternal factors, were collected for pH analysis. pH of MOM was analyzed over the course of lactation accounting for fortification status, postpartum day, and storage conditions.<h4>Results</h4>Mean pH of MOM was slightly acidic at 6.60 ± 0.28, which was significantly higher (p < 0.05) than other milk types. pH of MOM varied by fortification, postpartum day, and maternal vegetable/fiber intake. There was a significant interaction between fortification status and postpartum day; pH of MOM decreased over time, while pH of fortified MOM increased over time.<h4>Conclusion</h4>pH of human milk varied by type. pH of MOM was significantly associated with fortification status, postpartum day, and maternal vegetable/fiber intake.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-04T21:13:37.138Z","creation":"2025-04-04T21:13:37.138Z"},"accession":"S-EPMC9840648","cross_references":{"pubmed":["35978105"],"doi":["10.1038/s41372-022-01492-5"]}}