{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["68(7)"],"submitter":["Ali MU"],"pubmed_abstract":["<h4>Objective</h4>To summarize evidence from published systematic reviews evaluating the effect of polypharmacy interventions on clinical and intermediate outcomes. It also summarizes the adverse events that may occur as a result of these interventions.<h4>Data sources</h4>A literature search was conducted using the electronic databases MEDLINE, Embase, CINAHL, Cochrane Central, and Cochrane Database of Systematic Reviews (PROSPERO registration number: CRD42018085767).<h4>Study selection</h4>The search yielded a total of 21,329 citations, of which 619 were reviewed as full text and 5 met the selection criteria.<h4>Synthesis</h4>The polypharmacy interventions were found to produce statistically significant reductions in potentially inappropriate prescribing and improved medication adherence"],"journal":["Canadian family physician Medecin de famille canadien"],"pagination":["e215-e226"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9842141"],"repository":["biostudies-literature"],"pubmed_title":["Interventions to address polypharmacy in older adults living with multimorbidity: Review of reviews."],"pmcid":["PMC9842141"],"pubmed_authors":["Kenny M","Sherifali D","Ali MU","Lamarche L","Fitzpatrick-Lewis D","Raina P","Mangin D"],"additional_accession":[]},"is_claimable":false,"name":"Interventions to address polypharmacy in older adults living with multimorbidity: Review of reviews.","description":"<h4>Objective</h4>To summarize evidence from published systematic reviews evaluating the effect of polypharmacy interventions on clinical and intermediate outcomes. It also summarizes the adverse events that may occur as a result of these interventions.<h4>Data sources</h4>A literature search was conducted using the electronic databases MEDLINE, Embase, CINAHL, Cochrane Central, and Cochrane Database of Systematic Reviews (PROSPERO registration number: CRD42018085767).<h4>Study selection</h4>The search yielded a total of 21,329 citations, of which 619 were reviewed as full text and 5 met the selection criteria.<h4>Synthesis</h4>The polypharmacy interventions were found to produce statistically significant reductions in potentially inappropriate prescribing and improved medication adherence","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jul","modification":"2026-03-17T16:03:58.992Z","creation":"2025-04-04T19:48:13.111Z"},"accession":"S-EPMC9842141","cross_references":{"pubmed":["35831093"],"doi":["10.46747/cfp.6807e215"]}}