biostudies-literatureUnknown12(1)Hatanaka T<h4>Aims</h4>This retrospective study compared the survival between elderly and non-elderly patients.<h4>Methods</h4>A total of 5545 treatment-naive patients with hepatocellular carcinoma (HCC) who visited 7 different hospitals from January 2000 to December 2018 were included. Patients ≥80 years old were defined as elderly patients. We divided the patients into three groups based on the timing of the initial treatment: Early, middle, and late periods defined as 2000 to 2005, 2006 to 2012, and 2013 to 2018, respectively.<h4>Results</h4>There were 132 (8.9%), 405 (17.5%), and 388 (22.2%) elderly patients in the early, middle, and late period, respectively, showing a significant increase over time (p < 0.001). In both elderly and non-elderly patients, the median albumin-bilirubin score signifCancer medicine345-357https://www.ebi.ac.uk/biostudies/studies/S-EPMC9844645biostudies-literatureThe prognosis of elderly patients with hepatocellular carcinoma: A multi-center 19-year experience in Japan.PMC9844645Tada TKosaka HHiraoka AIshikawa TImai MReal-life Practice Experts for HCC (RELPEC) Study GroupNagano TShibata HTakaguchi KTsuji KToyoda HItobayashi EShimada NNouso KNaganuma ATanaka TTsutsui AKumada TKakizaki SHatanaka TYasuda SNakamura SKaibori MKariyama KfalseThe prognosis of elderly patients with hepatocellular carcinoma: A multi-center 19-year experience in Japan.<h4>Aims</h4>This retrospective study compared the survival between elderly and non-elderly patients.<h4>Methods</h4>A total of 5545 treatment-naive patients with hepatocellular carcinoma (HCC) who visited 7 different hospitals from January 2000 to December 2018 were included. Patients ≥80 years old were defined as elderly patients. We divided the patients into three groups based on the timing of the initial treatment: Early, middle, and late periods defined as 2000 to 2005, 2006 to 2012, and 2013 to 2018, respectively.<h4>Results</h4>There were 132 (8.9%), 405 (17.5%), and 388 (22.2%) elderly patients in the early, middle, and late period, respectively, showing a significant increase over time (p < 0.001). In both elderly and non-elderly patients, the median albumin-bilirubin score signif2023-01-01T00:00:00Z2023 Jan2025-04-18T18:17:48.517Z2025-04-07T05:54:28.37ZS-EPMC98446453560822610.1002/cam4.4850