{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Majuri T"],"funding":["University of Oulu including Oulu University Hospital","the Academy of Finland","the Iso-Mällinen Foundation","the Juho Vainio Foundation","the Yrjö Jahnsson Foundation","Oulu University Hospital","the University of Oulu Scholarship Foundation","University of Oulu","ERDF European Regional Development Fund"],"pagination":["65-76"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9845166"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["58(1)"],"pubmed_abstract":["<h4>Purpose</h4>Psychoses are associated with poor labour market attachment, but few studies have compared schizophrenia (SZ) and other psychoses (OP). Moreover, studies on long-term employment trajectories over individuals' working life courses are lacking. We compared 30 year employment trajectory patterns in a general population sample among individuals with SZ, OP, and those with no psychosis (NP).<h4>Methods</h4>Utilising the Northern Finland Birth Cohort 1966, we collected survey data on employment from ages 16 to 45 and detected individuals with register-based history of SZ (n = 62), OP (n = 87), or NP (n = 6464) until age 46. Through gender-specific latent class analyses on annual employment roles, we identified traditional, highly educated, self-employed, delayed and floundering employment trajectories with distinct socioeconomic characteristics. We addressed attrition by conducting weighted analyses.<h4>Results</h4>Floundering trajectories were common among individuals with SZ (79% of men, 73% of women) and OP (52% of men, 51% of women). In NP, a traditional employee trajectory was most common in men (31%), and a highly educated trajectory in women (28%). A history of psychosis was associated with heightened odds ratios (ORs; 95% confidence intervals (CIs)) for floundering trajectories in both men (SZ: 32.9 (13.3-81.4); OP: 7.4 (4.0-13.9)) and women (SZ: 9.9 (4.6-21.5); OP: 3.9 (2.1-7.1)) compared to NP. Weighted analyses produced similar results.<h4>Conclusion</h4>Most individuals with SZ or OP have floundering employee trajectories reflecting an elevated risk of unemployment and part-time work until midlife. These results indicate the importance of improving labour market attachment during the early phases of psychoses."],"journal":["Social psychiatry and psychiatric epidemiology"],"pubmed_title":["Employment trajectories until midlife in schizophrenia and other psychoses: the Northern Finland Birth Cohort 1966."],"pmcid":["PMC9845166"],"funding_grant_id":["539/2010 A31592","24000692","316563","24301140"],"pubmed_authors":["Haapea M","Majuri T","Alakokkare AE","Ala-Mursula L","Miettunen J","Nordstrom T","Jaaskelainen E"],"additional_accession":[]},"is_claimable":false,"name":"Employment trajectories until midlife in schizophrenia and other psychoses: the Northern Finland Birth Cohort 1966.","description":"<h4>Purpose</h4>Psychoses are associated with poor labour market attachment, but few studies have compared schizophrenia (SZ) and other psychoses (OP). Moreover, studies on long-term employment trajectories over individuals' working life courses are lacking. We compared 30 year employment trajectory patterns in a general population sample among individuals with SZ, OP, and those with no psychosis (NP).<h4>Methods</h4>Utilising the Northern Finland Birth Cohort 1966, we collected survey data on employment from ages 16 to 45 and detected individuals with register-based history of SZ (n = 62), OP (n = 87), or NP (n = 6464) until age 46. Through gender-specific latent class analyses on annual employment roles, we identified traditional, highly educated, self-employed, delayed and floundering employment trajectories with distinct socioeconomic characteristics. We addressed attrition by conducting weighted analyses.<h4>Results</h4>Floundering trajectories were common among individuals with SZ (79% of men, 73% of women) and OP (52% of men, 51% of women). In NP, a traditional employee trajectory was most common in men (31%), and a highly educated trajectory in women (28%). A history of psychosis was associated with heightened odds ratios (ORs; 95% confidence intervals (CIs)) for floundering trajectories in both men (SZ: 32.9 (13.3-81.4); OP: 7.4 (4.0-13.9)) and women (SZ: 9.9 (4.6-21.5); OP: 3.9 (2.1-7.1)) compared to NP. Weighted analyses produced similar results.<h4>Conclusion</h4>Most individuals with SZ or OP have floundering employee trajectories reflecting an elevated risk of unemployment and part-time work until midlife. These results indicate the importance of improving labour market attachment during the early phases of psychoses.","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-03-17T15:22:26.487Z","creation":"2025-04-06T01:07:12.717Z"},"accession":"S-EPMC9845166","cross_references":{"pubmed":["35796815"],"doi":["10.1007/s00127-022-02327-6"]}}