{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Zhang L"],"pubmed_abstract":["<h4>Background</h4>The lateral intersecting margin (dog-ear) was a weak spot of the double stapled technique (DST), We designed \"dog-ear\" invagination anastomosis (DAIA), which could eliminate the \"dog-ear\" in laparoscopic anterior resection.<h4>Patients and methods</h4>A total of 202 patients underwent elective curative LLAR + DST (<i>n</i> = 143) or LLAR + DAIA (<i>n</i> = 59) were enrolled in the study. Propensity score matching (PSM) was used to minimize the adverse effects. The clinical data between LLAR + DST and LLAR + DAIA was compared, and the effect of factors on overall survival (OS) and disease-free survival (DFS) was analyzed.<h4>Results</h4>After PSM, 53 pairs of the LLRA + DST and LLRA + DAIA patients were enrolled in the study. The LLRA + DAIA group has a higher level (3.50 ± 1.03 vs. 2.87 ± 1.10, <i>P</i> = 0.01) of the anastomosis than that of the LLRA + DST group. Patients in LLAR + DAIA group have a lower incidence of protecting loop ileostomy compared to LLAR + DST group (20.75% vs. 5.66%, <i>P</i> < 0.05). The LLRA + DAIA patients presented better rates of LARS compare to LLRA + DST patients at 6 months (major LARS 37.74% (<i>n</i> = 20) vs. 67.93% (<i>n</i> = 36); <i>P</i> = 0.007) and 12 months (major LARS 13.21% (<i>n</i> = 7) vs. 20.37% (<i>n</i> = 11); <i>P</i> = 0.03) after surgery. The OS and DFS rates were similar (<i>P</i> > 0.05).<h4>Conclusion</h4>Laparoscopic low anterior resection with \"dog-ear\" invagination anastomosis technique are well-established procedures for patients with low rectal cancer. \"Dog-ear\" invagination anastomosis technique may reduce the incidence of protecting loop ileostomy and significantly affect LARS score, and demonstrate a positive impact on the quality of life after surgery."],"journal":["Frontiers in surgery"],"pagination":["1038873"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9852756"],"repository":["biostudies-literature"],"pubmed_title":["Short- and long-term outcomes of laparoscopic low anterior resection with \"dog ear\" invagination anastomosis for mid and distal rectal cancer a propensity score matched analysis."],"pmcid":["PMC9852756"],"pubmed_authors":["Lv X","Xie Z","Gong L","Zhang L"],"additional_accession":[]},"is_claimable":false,"name":"Short- and long-term outcomes of laparoscopic low anterior resection with \"dog ear\" invagination anastomosis for mid and distal rectal cancer a propensity score matched analysis.","description":"<h4>Background</h4>The lateral intersecting margin (dog-ear) was a weak spot of the double stapled technique (DST), We designed \"dog-ear\" invagination anastomosis (DAIA), which could eliminate the \"dog-ear\" in laparoscopic anterior resection.<h4>Patients and methods</h4>A total of 202 patients underwent elective curative LLAR + DST (<i>n</i> = 143) or LLAR + DAIA (<i>n</i> = 59) were enrolled in the study. Propensity score matching (PSM) was used to minimize the adverse effects. The clinical data between LLAR + DST and LLAR + DAIA was compared, and the effect of factors on overall survival (OS) and disease-free survival (DFS) was analyzed.<h4>Results</h4>After PSM, 53 pairs of the LLRA + DST and LLRA + DAIA patients were enrolled in the study. The LLRA + DAIA group has a higher level (3.50 ± 1.03 vs. 2.87 ± 1.10, <i>P</i> = 0.01) of the anastomosis than that of the LLRA + DST group. Patients in LLAR + DAIA group have a lower incidence of protecting loop ileostomy compared to LLAR + DST group (20.75% vs. 5.66%, <i>P</i> < 0.05). The LLRA + DAIA patients presented better rates of LARS compare to LLRA + DST patients at 6 months (major LARS 37.74% (<i>n</i> = 20) vs. 67.93% (<i>n</i> = 36); <i>P</i> = 0.007) and 12 months (major LARS 13.21% (<i>n</i> = 7) vs. 20.37% (<i>n</i> = 11); <i>P</i> = 0.03) after surgery. The OS and DFS rates were similar (<i>P</i> > 0.05).<h4>Conclusion</h4>Laparoscopic low anterior resection with \"dog-ear\" invagination anastomosis technique are well-established procedures for patients with low rectal cancer. \"Dog-ear\" invagination anastomosis technique may reduce the incidence of protecting loop ileostomy and significantly affect LARS score, and demonstrate a positive impact on the quality of life after surgery.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-22T01:07:41.676Z","creation":"2025-04-05T19:49:45.198Z"},"accession":"S-EPMC9852756","cross_references":{"pubmed":["36684252"],"doi":["10.3389/fsurg.2022.1038873"]}}