{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nora LC"],"funding":["FAPESP","CNPq"],"pagination":["1069443"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9853887"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13"],"pubmed_abstract":["The demand for robust microbial cell factories that produce valuable biomaterials while resisting stresses imposed by current bioprocesses is rapidly growing. <i>Rhodosporidium toruloides</i> is an emerging host that presents desirable features for bioproduction, since it can grow in a wide range of substrates and tolerate a variety of toxic compounds. To explore <i>R. toruloides</i> suitability for application as a cell factory in biorefineries, we sought to understand the transcriptional responses of this yeast when growing under experimental settings that simulated those used in biofuels-related industries. Thus, we performed RNA sequencing of the oleaginous, carotenogenic yeast in different contexts. The first ones were stress-related: two conditions of high temperature (37 and 42°C) a"],"journal":["Frontiers in microbiology"],"pubmed_title":["Mining novel <i>cis</i>-regulatory elements from the emergent host <i>Rhodosporidium toruloides</i> using transcriptomic data."],"pmcid":["PMC9853887"],"funding_grant_id":["2020/02207-5","2019/15675-0","2019/05026-4","2021/01748-5","2017/18922-2","140212/2019-1","2019/04942-7"],"pubmed_authors":["Nora LC","Santana IP","Cassiano MHA","Silva-Rocha R","da Silva RR","Guazzaroni ME"],"additional_accession":[]},"is_claimable":false,"name":"Mining novel <i>cis</i>-regulatory elements from the emergent host <i>Rhodosporidium toruloides</i> using transcriptomic data.","description":"The demand for robust microbial cell factories that produce valuable biomaterials while resisting stresses imposed by current bioprocesses is rapidly growing. <i>Rhodosporidium toruloides</i> is an emerging host that presents desirable features for bioproduction, since it can grow in a wide range of substrates and tolerate a variety of toxic compounds. To explore <i>R. toruloides</i> suitability for application as a cell factory in biorefineries, we sought to understand the transcriptional responses of this yeast when growing under experimental settings that simulated those used in biofuels-related industries. Thus, we performed RNA sequencing of the oleaginous, carotenogenic yeast in different contexts. The first ones were stress-related: two conditions of high temperature (37 and 42°C) a","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-05-28T18:40:44.87Z","creation":"2025-02-19T04:45:46.319Z"},"accession":"S-EPMC9853887","cross_references":{"pubmed":["36687612"],"doi":["10.3389/fmicb.2022.1069443"]}}