biostudies-literatureUnknown9Liu H<h4>Objective</h4>Trigeminal neuralgia (TN) is one of the leading causes of facial pain and seriously affects patients' quality of life. Foramen ovale (FO) radiofrequency thermocoagulation is a classic approach for the treatment of TN that has failed pharmacological therapy. This study summarized the safety and efficacy of transforaminal radiofrequency thermocoagulation for TN by comparing puncture approaches or guidance techniques, thereby providing higher-quality clinical evidence.<h4>Methods</h4>Databases including PubMed, Embase, Cochrane Library, CNKI, and Wanfang were searched for relevant studies published before May 2022. Relevant data were extracted for analysis to compare methodological variables and clinical outcomes.<h4>Results</h4>This meta-analysis included 27 studies with a Frontiers in surgery1024619https://www.ebi.ac.uk/biostudies/studies/S-EPMC9853901biostudies-literaturePuncture approaches and guidance techniques of radiofrequency thermocoagulation through foramen Ovale for primary trigeminal neuralgia: Systematic review and meta-analysis.PMC9853901Liu HXu LZhao WfalsePuncture approaches and guidance techniques of radiofrequency thermocoagulation through foramen Ovale for primary trigeminal neuralgia: Systematic review and meta-analysis.<h4>Objective</h4>Trigeminal neuralgia (TN) is one of the leading causes of facial pain and seriously affects patients' quality of life. Foramen ovale (FO) radiofrequency thermocoagulation is a classic approach for the treatment of TN that has failed pharmacological therapy. This study summarized the safety and efficacy of transforaminal radiofrequency thermocoagulation for TN by comparing puncture approaches or guidance techniques, thereby providing higher-quality clinical evidence.<h4>Methods</h4>Databases including PubMed, Embase, Cochrane Library, CNKI, and Wanfang were searched for relevant studies published before May 2022. Relevant data were extracted for analysis to compare methodological variables and clinical outcomes.<h4>Results</h4>This meta-analysis included 27 studies with a 2022-01-01T00:00:00Z20222026-03-17T15:23:49.142Z2025-04-05T22:51:34.582ZS-EPMC98539013668412110.3389/fsurg.2022.1024619