{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(1)"],"submitter":["Cheng MJ"],"pubmed_abstract":["In our continued search for bioactive metabolites from cultures of rare <i>Actinobacteria</i> resources from all over Taiwan and various natural ecological environments, an active antimicrobial strain of <i>Acrocarpospora punica</i> 04107M was collected in Taitung County in Taiwan and prepared from soil. The bioassay-guided fractionation of the BuOH extract of a culture broth from <i>A</i>. <i>punica</i> 04107M led to the isolation of five previously undescribed compounds: Acrocarposporins A-E (Compounds <b>1</b>-<b>5</b>). All the constituents were confirmed by HRESIMS and 1D- and 2D-NMR spectroscopy. Their antifungal activity was also evaluated. Our results showed that four constituents (Compounds <b>1</b>, <b>2</b>, <b>4</b>, and <b>5</b>) possessed mild antifungal activity against <i>A"],"journal":["Antibiotics (Basel, Switzerland)"],"pagination":["95"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9854854"],"repository":["biostudies-literature"],"pubmed_title":["Antifungal Activities of Compounds Produced by Newly Isolated <i>Acrocarpospora</i> Strains."],"pmcid":["PMC9854854"],"pubmed_authors":["Wu MD","Leu JY","Tseng M","Cheng MJ","Chen JJ"],"additional_accession":[]},"is_claimable":false,"name":"Antifungal Activities of Compounds Produced by Newly Isolated <i>Acrocarpospora</i> Strains.","description":"In our continued search for bioactive metabolites from cultures of rare <i>Actinobacteria</i> resources from all over Taiwan and various natural ecological environments, an active antimicrobial strain of <i>Acrocarpospora punica</i> 04107M was collected in Taitung County in Taiwan and prepared from soil. The bioassay-guided fractionation of the BuOH extract of a culture broth from <i>A</i>. <i>punica</i> 04107M led to the isolation of five previously undescribed compounds: Acrocarposporins A-E (Compounds <b>1</b>-<b>5</b>). All the constituents were confirmed by HRESIMS and 1D- and 2D-NMR spectroscopy. Their antifungal activity was also evaluated. Our results showed that four constituents (Compounds <b>1</b>, <b>2</b>, <b>4</b>, and <b>5</b>) possessed mild antifungal activity against <i>A","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-22T01:07:37.02Z","creation":"2025-04-05T19:49:03.57Z"},"accession":"S-EPMC9854854","cross_references":{"pubmed":["36671296"],"doi":["10.3390/antibiotics12010095"]}}