{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhu J"],"funding":["NIDDK NIH HHS","NHLBI NIH HHS"],"pagination":["e2250621"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9856626"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["6(1)"],"pubmed_abstract":["<h4>Importance</h4>The associations of B vitamin status with metabolic syndrome (MetS) incidence among the US population remain unclear.<h4>Objective</h4>To investigate intakes and serum concentrations of folate, vitamin B6, and vitamin B12 in association with MetS risk in a large US cohort.<h4>Design, setting, and participants</h4>This prospective study included Black and White young adults in the US who were enrolled from 1985 to 1986 and studied until 2015 to 2016. Diet was assessed using a validated diet history at examination years 0, 7, and 20. Serum concentrations of folate, vitamin B6, and vitamin B12 were assayed at examination years 0, 7, and 15 in a subset of 1430 participants. MetS was ascertained by clinic and laboratory measurements and self-reported medication use. Data were"],"journal":["JAMA network open"],"pubmed_title":["Folate, Vitamin B6, and Vitamin B12 Status in Association With Metabolic Syndrome Incidence."],"pmcid":["PMC9856626"],"funding_grant_id":["HHSN268201800005I","HHSN268201800004I","HHSN268201800007I","HHSN268201800006I","R01 DK116603","HHSN268201800003I"],"pubmed_authors":["Shikany JM","Lu L","Zhu J","Chen C","Kahe K","D'Alton ME"],"additional_accession":[]},"is_claimable":false,"name":"Folate, Vitamin B6, and Vitamin B12 Status in Association With Metabolic Syndrome Incidence.","description":"<h4>Importance</h4>The associations of B vitamin status with metabolic syndrome (MetS) incidence among the US population remain unclear.<h4>Objective</h4>To investigate intakes and serum concentrations of folate, vitamin B6, and vitamin B12 in association with MetS risk in a large US cohort.<h4>Design, setting, and participants</h4>This prospective study included Black and White young adults in the US who were enrolled from 1985 to 1986 and studied until 2015 to 2016. Diet was assessed using a validated diet history at examination years 0, 7, and 20. Serum concentrations of folate, vitamin B6, and vitamin B12 were assayed at examination years 0, 7, and 15 in a subset of 1430 participants. MetS was ascertained by clinic and laboratory measurements and self-reported medication use. Data were","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2026-07-16T20:12:03.957Z","creation":"2025-04-06T02:21:35.673Z"},"accession":"S-EPMC9856626","cross_references":{"pubmed":["36630134"],"doi":["10.1001/jamanetworkopen.2022.50621"]}}