{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(2)"],"submitter":["Liu X"],"pubmed_abstract":["Propolis is resinous natural product produced by Western honeybees using beeswax and plant and bud exudates, which has a wide range of biological activities, including antioxidation, antibacterial, anti-inflammation, immune regulation, antitumor, and so on. Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer, and accounts for about 30% of all lymphomas. The effect of poplar propolis on DLBCL has not been reported. The IC<sub>50</sub> of propolis on the proliferation of DLBCL SU-DHL-2 cell line and its proteins and gene expressions were detected by CCK-8 kit, label-free proteomic, and RT-PCR. The results showed that the IC<sub>50</sub> of propolis at the 5 × l05/mL cell for 24 h was 5.729 μg/mL. Label-free-based proteomics analysis showed that there were 115 differentially express"],"journal":["Foods (Basel, Switzerland)"],"pagination":["283"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9857396"],"repository":["biostudies-literature"],"pubmed_title":["Antitumor Effects of Poplar Propolis on DLBCL SU-DHL-2 Cells."],"pmcid":["PMC9857396"],"pubmed_authors":["Liu X","Yang W","Tian Y","Miao X","Yang A","Zhang C"],"additional_accession":[]},"is_claimable":false,"name":"Antitumor Effects of Poplar Propolis on DLBCL SU-DHL-2 Cells.","description":"Propolis is resinous natural product produced by Western honeybees using beeswax and plant and bud exudates, which has a wide range of biological activities, including antioxidation, antibacterial, anti-inflammation, immune regulation, antitumor, and so on. Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer, and accounts for about 30% of all lymphomas. The effect of poplar propolis on DLBCL has not been reported. The IC<sub>50</sub> of propolis on the proliferation of DLBCL SU-DHL-2 cell line and its proteins and gene expressions were detected by CCK-8 kit, label-free proteomic, and RT-PCR. The results showed that the IC<sub>50</sub> of propolis at the 5 × l05/mL cell for 24 h was 5.729 μg/mL. Label-free-based proteomics analysis showed that there were 115 differentially express","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-22T09:07:25.302Z","creation":"2024-11-21T01:02:48.386Z"},"accession":"S-EPMC9857396","cross_references":{"pubmed":["36673375"],"doi":["10.3390/foods12020283"]}}