{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xu J"],"funding":["Guizhou Provincial Science and Technology Project","Guizhou Provincial Agricultural Major Industrial Scientific Research Project"],"pagination":["113"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9858937"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(1)"],"pubmed_abstract":["In this study, Xiangsu hybrid pig growth traits were evaluated via <i>PRKAA2</i> and <i>MSMB</i> as candidate genes. Sanger sequencing revealed three mutation sites in <i>PRKAA2</i>, namely, g.42101G>T, g.60146A>T, and g.61455G>A, and all these sites were intronic mutations. Moreover, six mutation sites were identified in <i>MSMB</i>: intronic g.4374G>T, exonic g.4564T>C, exonic g.6378G>A, exonic g.6386C>T, intronic g.8643G>A, and intronic g.8857A>G. Association analysis revealed that g.42101G>T, g.60146A>T, g.61455G>A, g.4374G>T, g.4564T>C, g.6378G>A, g.6386C>T, g.8643G>A, and g.8857A>G showed different relationship patterns among body weight, body length, body height, chest circumference, abdominal circumference, tube circumference, and chest depth. Real-time polymerase chain reaction re"],"journal":["Genes"],"pubmed_title":["Association Analysis of <i>PRKAA2</i> and <i>MSMB</i> Polymorphisms and Growth Traits of Xiangsu Hybrid Pigs."],"pmcid":["PMC9858937"],"funding_grant_id":["QKHFQ-2018,4007, (002)","QKHKYZ-2019,011"],"pubmed_authors":["Ruan Y","Dai L","Xiao M","Huang J","Shi P","Xu H","Xu J","Sun J"],"additional_accession":[]},"is_claimable":false,"name":"Association Analysis of <i>PRKAA2</i> and <i>MSMB</i> Polymorphisms and Growth Traits of Xiangsu Hybrid Pigs.","description":"In this study, Xiangsu hybrid pig growth traits were evaluated via <i>PRKAA2</i> and <i>MSMB</i> as candidate genes. Sanger sequencing revealed three mutation sites in <i>PRKAA2</i>, namely, g.42101G>T, g.60146A>T, and g.61455G>A, and all these sites were intronic mutations. Moreover, six mutation sites were identified in <i>MSMB</i>: intronic g.4374G>T, exonic g.4564T>C, exonic g.6378G>A, exonic g.6386C>T, intronic g.8643G>A, and intronic g.8857A>G. Association analysis revealed that g.42101G>T, g.60146A>T, g.61455G>A, g.4374G>T, g.4564T>C, g.6378G>A, g.6386C>T, g.8643G>A, and g.8857A>G showed different relationship patterns among body weight, body length, body height, chest circumference, abdominal circumference, tube circumference, and chest depth. Real-time polymerase chain reaction re","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-05T00:16:18.018Z","creation":"2024-11-05T15:11:21.448Z"},"accession":"S-EPMC9858937","cross_references":{"pubmed":["36672854"],"doi":["10.3390/genes14010113"]}}