{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["24(2)"],"submitter":["Syed SA"],"pubmed_abstract":["Oral squamous cell carcinomas (OSCC) remain a major healthcare burden in Asian countries. In Pakistan alone, it is the most common cancer in males and second only to breast cancer in females. Alarmingly, treatment options for OSCC remain limited. With this context, investigations made to explore the inflammatory <i>milieu</i> of OSCC become highly relevant, with the hope of practicing immunotherapeutic approaches to address this highly prevalent tumor. We investigated the newly identified innate lymphoid cells (ILCs) and associated cytokines in well-defined human oral squamous cell carcinoma (OSCC) as well as in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced murine model of OSCC using flow cytometry and quantitative real-time polymerase chain reaction (qPCR). We further went on to explore"],"journal":["International journal of molecular sciences"],"pagination":["1627"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9865302"],"repository":["biostudies-literature"],"pubmed_title":["Differential Regulation of Innate Lymphoid Cells in Human and Murine Oral Squamous Cell Carcinoma."],"pmcid":["PMC9865302"],"pubmed_authors":["Khan BA","Qureshi MA","Syed SA","Safdar J","Khyani IAM","Kumar R","Khan S"],"additional_accession":[]},"is_claimable":false,"name":"Differential Regulation of Innate Lymphoid Cells in Human and Murine Oral Squamous Cell Carcinoma.","description":"Oral squamous cell carcinomas (OSCC) remain a major healthcare burden in Asian countries. In Pakistan alone, it is the most common cancer in males and second only to breast cancer in females. Alarmingly, treatment options for OSCC remain limited. With this context, investigations made to explore the inflammatory <i>milieu</i> of OSCC become highly relevant, with the hope of practicing immunotherapeutic approaches to address this highly prevalent tumor. We investigated the newly identified innate lymphoid cells (ILCs) and associated cytokines in well-defined human oral squamous cell carcinoma (OSCC) as well as in a 7,12-dimethylbenz[a]anthracene (DMBA)-induced murine model of OSCC using flow cytometry and quantitative real-time polymerase chain reaction (qPCR). We further went on to explore","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-22T01:09:26.085Z","creation":"2025-04-05T19:49:51.541Z"},"accession":"S-EPMC9865302","cross_references":{"pubmed":["36675138"],"doi":["10.3390/ijms24021627"]}}