biostudies-literatureUnknown9Nieman DC<h4>Introduction</h4>This investigation determined if 4-weeks ingestion of nutrient-dense almonds mitigated post-exercise inflammation and muscle soreness and damage.<h4>Methods</h4>An acute 90-min of eccentric exercise (90-EE) was used to induce muscle damage in 64 non-obese adults not engaging in regular resistance training (ages 30-65 years, BMI < 30 kg/m²). Using a parallel group design, participants were randomized to almond (AL) (57 g/d) or cereal bar (CB) (calorie matched) treatment groups for a 4-week period prior to the 90-EE (17 exercises). Blood and 24-h urine samples were collected before and after supplementation, with additional blood samples collected immediately post-90-EE, and then daily during 4 additional days of recovery. Changes in plasma oxylipins, urinary Frontiers in nutrition1042719https://www.ebi.ac.uk/biostudies/studies/S-EPMC9868138biostudies-literatureAlmond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise.PMC9868138Kasote DMSakaguchi CALkhagva AKay CDWeldemariam MMOmar AMNieman DCZhang QfalseAlmond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise.<h4>Introduction</h4>This investigation determined if 4-weeks ingestion of nutrient-dense almonds mitigated post-exercise inflammation and muscle soreness and damage.<h4>Methods</h4>An acute 90-min of eccentric exercise (90-EE) was used to induce muscle damage in 64 non-obese adults not engaging in regular resistance training (ages 30-65 years, BMI < 30 kg/m²). Using a parallel group design, participants were randomized to almond (AL) (57 g/d) or cereal bar (CB) (calorie matched) treatment groups for a 4-week period prior to the 90-EE (17 exercises). Blood and 24-h urine samples were collected before and after supplementation, with additional blood samples collected immediately post-90-EE, and then daily during 4 additional days of recovery. Changes in plasma oxylipins, urinary 2022-01-01T00:00:00Z20222025-04-04T19:48:21.055Z2024-11-21T01:04:39.192ZS-EPMC98681383669846910.3389/fnut.2022.1042719