{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Sun X"],"pubmed_abstract":["The main challenges in bio-catalysis of d-phenyllactic acid (D-PLA) are poor tolerance of lactate dehydrogenase (LDH) to harsh environmental conditions and inability to recycle the catalyst. A novel magnetic framework composite was prepared as solid support for the immobilization of enzymes <i>via</i> one-pot encapsulation in this study. LDH/MNPs@MAF-7 was synthesized by the one-pot encapsulation of both LDH and magnetic nanoparticles (MNPs) in MAF-7. The LDH/MNPs@MAF-7 showed stable biological activity for the efficient biosynthesis of D-PLA. The structure and morphology of LDH/MNPs@MAF-7 were systematically characterized by SEM, FT-IR, XRD, VSM, XPS, TGA and N<sub>2</sub> sorption. These indicated that LDH/MNPs@MAF-7 was successfully synthesized, exhibiting enhanced resistance to acid an"],"journal":["Frontiers in bioengineering and biotechnology"],"pagination":["1124450"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9868447"],"repository":["biostudies-literature"],"pubmed_title":["One-pot encapsulation of lactate dehydrogenase and Fe<sub>3</sub>O<sub>4</sub> nanoparticles into a metal-organic framework: A novel magnetic recyclable biocatalyst for the synthesis of D-phenyllactic acid."],"pmcid":["PMC9868447"],"pubmed_authors":["Hu J","Huang H","Fu Y","Luo X","Sun X","Wang Y"],"additional_accession":[]},"is_claimable":false,"name":"One-pot encapsulation of lactate dehydrogenase and Fe<sub>3</sub>O<sub>4</sub> nanoparticles into a metal-organic framework: A novel magnetic recyclable biocatalyst for the synthesis of D-phenyllactic acid.","description":"The main challenges in bio-catalysis of d-phenyllactic acid (D-PLA) are poor tolerance of lactate dehydrogenase (LDH) to harsh environmental conditions and inability to recycle the catalyst. A novel magnetic framework composite was prepared as solid support for the immobilization of enzymes <i>via</i> one-pot encapsulation in this study. LDH/MNPs@MAF-7 was synthesized by the one-pot encapsulation of both LDH and magnetic nanoparticles (MNPs) in MAF-7. The LDH/MNPs@MAF-7 showed stable biological activity for the efficient biosynthesis of D-PLA. The structure and morphology of LDH/MNPs@MAF-7 were systematically characterized by SEM, FT-IR, XRD, VSM, XPS, TGA and N<sub>2</sub> sorption. These indicated that LDH/MNPs@MAF-7 was successfully synthesized, exhibiting enhanced resistance to acid an","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-18T12:00:33.949Z","creation":"2024-10-15T07:41:50.637Z"},"accession":"S-EPMC9868447","cross_references":{"pubmed":["36698639"],"doi":["10.3389/fbioe.2022.1124450"]}}