biostudies-literatureUnknown9Cann PAgence Nationale de la Recherche<h4>Introduction</h4>Under temperate latitudes, reproduction in <i>Ovis aries</i> displays a marked seasonality, governed by the photoperiod. In natural conditions, the transition between sexual rest and sexual activity in both sexes is induced by the decrease of day light. Meanwhile, specific odors emitted by a sexually active male are able to reactivate the gonadotropic axis of anovulatory ewes. This physiological effect is called "male effect", precisely ram effect in the ovine species. We have previously shown that the secreted proteins, namely Olfactory Binding Proteins (OBP), contained in the nasal mucus constitute the olfactory secretome (OS), the composition of which is determined by the status of oestrus cycle of females and differs between sexual rest and sexual activity periods.Frontiers in veterinary science1033412https://www.ebi.ac.uk/biostudies/studies/S-EPMC9868937biostudies-literatureVariation of ewe olfactory secretome during a ram effect.PMC9868937Cann PLe Danvic CNagnan-Le Meillour PChesneau DPorte CKeller MfalseVariation of ewe olfactory secretome during a ram effect.<h4>Introduction</h4>Under temperate latitudes, reproduction in <i>Ovis aries</i> displays a marked seasonality, governed by the photoperiod. In natural conditions, the transition between sexual rest and sexual activity in both sexes is induced by the decrease of day light. Meanwhile, specific odors emitted by a sexually active male are able to reactivate the gonadotropic axis of anovulatory ewes. This physiological effect is called "male effect", precisely ram effect in the ovine species. We have previously shown that the secreted proteins, namely Olfactory Binding Proteins (OBP), contained in the nasal mucus constitute the olfactory secretome (OS), the composition of which is determined by the status of oestrus cycle of females and differs between sexual rest and sexual activity periods.2022-01-01T00:00:00Z20222026-06-27T03:22:15.415Z2025-04-05T21:06:49.489ZS-EPMC98689373669932210.3389/fvets.2022.1033412