biostudies-literatureUnknown21(1)Wu J<h4>Background</h4>Left ventricular (LV) myocardial work index (WI) and work efficiency (WE) have become the latest indicators for assessing LV function. Reference ranges for normal LV segmental WI and WE have not been established.<h4>Methods</h4>Four hundred eleven healthy Asian subjects (47% men, median age: 35 years) were enrolled prospectively. WI and WE were analysed using the LV pressure-strain loop (LVPSL) with specific software.<h4>Results</h4>WI and WE differed significantly between segments as well as between walls and levels of the left ventricle. The anteroseptal basal segment had the lowest WI and WE (1440 mmHg ± 324 and 92% [88-96], respectively) among the eighteen segments. Significant WI and WE differences were found between sexes and age groups. No correlation was observedCardiovascular ultrasound2https://www.ebi.ac.uk/biostudies/studies/S-EPMC9869544biostudies-literatureEchocardiographic reference ranges for noninvasive left ventricular 18-segment myocardial work index and work efficiency in a healthy Asian population.PMC9869544Gao QWu JLin BHuang XSu MHuang KChen XJing BWang XTang YfalseEchocardiographic reference ranges for noninvasive left ventricular 18-segment myocardial work index and work efficiency in a healthy Asian population.<h4>Background</h4>Left ventricular (LV) myocardial work index (WI) and work efficiency (WE) have become the latest indicators for assessing LV function. Reference ranges for normal LV segmental WI and WE have not been established.<h4>Methods</h4>Four hundred eleven healthy Asian subjects (47% men, median age: 35 years) were enrolled prospectively. WI and WE were analysed using the LV pressure-strain loop (LVPSL) with specific software.<h4>Results</h4>WI and WE differed significantly between segments as well as between walls and levels of the left ventricle. The anteroseptal basal segment had the lowest WI and WE (1440 mmHg ± 324 and 92% [88-96], respectively) among the eighteen segments. Significant WI and WE differences were found between sexes and age groups. No correlation was observed2023-01-01T00:00:00Z2023 Jan2025-05-31T23:47:04.148Z2025-02-19T02:55:41.825ZS-EPMC98695443668306510.1186/s12947-023-00299-4