biostudies-literatureUnknown9Laghlam D<h4>Background</h4>Takotsubo cardiomyopathy (TTC) is a rare entity after cardiac surgery.<h4>Aims</h4>To describe patients' profile who developed postoperative TTC after cardiac surgery, management, and outcomes.<h4>Methods</h4>We performed a systematic literature search to extract cases of TTC after adult cardiac surgery (from 1990 to 2021). Additionally, we extracted all cases of TTC in a prospective single-center cohort database of 10,000+ patients (from 2007 to 2019). We then combined all cases in a single cohort to describe its clinical features.<h4>Results</h4>From 694 screened articles, we retained 71 individual cases published in 20 distinct articles (19 cases reports and 1 case-series). We combined these to 10 cases extracted from our cohort [among 10,682 patients (0.09%)]. Overall, we included 81 cases. Patients were aged 68 ± 10 years-old and 64/81 (79%) were women. Surgery procedures included mitral valve and/or tricuspid valve surgery in 70/81, 86%. TTC was diagnosed in the first days after surgery [median 4 (1-4) days]. Incidence of cardiogenic shock, defined as requirement of vasopressor and/or inotropic support was 24/29, 83% (data available on 29/81 patients). Refractory cardiogenic appeared in 5/81, 6% who required implantation of arterio-venous extra-corporeal membrane oxygenation, and 6/81, 7%, intra-aortic balloon pump. In-hospital mortality was 5/81, 6%.<h4>Conclusion</h4>This systematic review, based on case reports and case series, showed that postoperative TTC appears as a rare complication after cardiac surgery and mainly occurred after mitral and/or tricuspid valve repair procedures. In this population, TTC is associated with high rate of cardiogenic shock.Frontiers in cardiovascular medicine1067444https://www.ebi.ac.uk/biostudies/studies/S-EPMC9871635biostudies-literatureTakotsubo cardiomyopathy after cardiac surgery: A case-series and systematic review of literature.PMC9871635Touboul OBrusset ADib JCEstagnasie PNguyen LSLaghlam DBaccouche MSquara PHerry MfalseTakotsubo cardiomyopathy after cardiac surgery: A case-series and systematic review of literature.<h4>Background</h4>Takotsubo cardiomyopathy (TTC) is a rare entity after cardiac surgery.<h4>Aims</h4>To describe patients' profile who developed postoperative TTC after cardiac surgery, management, and outcomes.<h4>Methods</h4>We performed a systematic literature search to extract cases of TTC after adult cardiac surgery (from 1990 to 2021). Additionally, we extracted all cases of TTC in a prospective single-center cohort database of 10,000+ patients (from 2007 to 2019). We then combined all cases in a single cohort to describe its clinical features.<h4>Results</h4>From 694 screened articles, we retained 71 individual cases published in 20 distinct articles (19 cases reports and 1 case-series). We combined these to 10 cases extracted from our cohort [among 10,682 patients (0.09%)]. Overall, we included 81 cases. Patients were aged 68 ± 10 years-old and 64/81 (79%) were women. Surgery procedures included mitral valve and/or tricuspid valve surgery in 70/81, 86%. TTC was diagnosed in the first days after surgery [median 4 (1-4) days]. Incidence of cardiogenic shock, defined as requirement of vasopressor and/or inotropic support was 24/29, 83% (data available on 29/81 patients). Refractory cardiogenic appeared in 5/81, 6% who required implantation of arterio-venous extra-corporeal membrane oxygenation, and 6/81, 7%, intra-aortic balloon pump. In-hospital mortality was 5/81, 6%.<h4>Conclusion</h4>This systematic review, based on case reports and case series, showed that postoperative TTC appears as a rare complication after cardiac surgery and mainly occurred after mitral and/or tricuspid valve repair procedures. In this population, TTC is associated with high rate of cardiogenic shock.2022-01-01T00:00:00Z20222025-04-22T06:15:03.34Z2025-04-05T21:39:50.503ZS-EPMC98716353670445510.3389/fcvm.2022.1067444